Hexamethyldisilazane

CAS 999-97-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$537M

Top sourceChina 39%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293190 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293190, which covers 378 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 39%ChinaDE 17%GermanyIT 9%ItalyIN 7%IndiaJP 7%Japan

Ireland
Netherlands
Switzerland
Monaco
Ukraine
Spain
Mexico
Poland
Indonesia
Armenia
Israel
Sweden
Australia
Czech Republic
Hungary
Brunei
Hong Kong
Brazil
Thailand
Argentina
Finland
Austria
Latvia

EPA-registered manufacturers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Kcc · KR South Korea

Ab Specialty Silicones

Dow Chemical

Mom Holding

Domestic parents -- activity not disclosed (5)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Elkem Silicones Usa

Fujifilm Holdings America

Milliken &

Pht International

Wacker Chemical Corporation - Headquarters

EPA-registered importers (10)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Asia Union Electronic Chemical · TW Taiwan

Mitsubishi Chemical Group · JP Japan

Shin-Etsu Chemical · JP Japan

Vencorex Holding · FR France

Asia Union Electronic Chemicals - Reno

Show all 10

Brb North America

Fci

Mitsubishi Chemical America

Shin-Etsu Microsi

Vencorex Us

Why It Matters

Sectors

HealthElectronicsConstructionMetals & MiningPlastics & RubberConsumer ProductsPaints & CoatingsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 13 sectors as 9 functional roles.

•Adhesion/cohesion promoter in Other (100%)Processing—repackaging
•Adhesion/cohesion promoter in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into article
•Intermediate in Miscellaneous Manufacturing (10%)Processing as a reactant
•Intermediate in All Other Chemical Product and Preparation Manufacturing (90%)Processing as a reactant
•Intermediate in Synthetic Rubber Manufacturing (35%)Processing as a reactant
•Intermediate in Plastics Material and Resin Manufacturing (23%)Processing as a reactant
•Intermediate in All Other Basic Organic Chemical Manufacturing (9%)Processing as a reactant
•Intermediate in Computer and Electronic Product Manufacturing (25%)Processing as a reactant
•Binder in Paint and Coating Manufacturing (50%)Processing as a reactant
•Waterproofing agent in Paint and Coating Manufacturing (50%)Processing as a reactant
•Intermediate in Pharmaceutical and Medicine ManufacturingProcessing as a reactant
•Intermediate in All Other Basic Inorganic Chemical Manufacturing (100%)Processing as a reactant
•Surface modifier in Rubber Product Manufacturing (80%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (40%)Processing—incorporation into formulation, mixture, or reaction product
•Polymerization promoter in Paint and Coating Manufacturing (100%)Processing as a reactant
•Solvent in Computer and Electronic Product Manufacturing (100%)Use—non-incorporative activities
•Viscosity modifiers in All Other Chemical Product and Preparation Manufacturing (90%)Processing—incorporation into formulation, mixture, or reaction product
•Semiconductor and photovoltaic agent in Wholesale and Retail Trade (100%)Use—non-incorporative activities

Chemical Identity

CAS999-97-3

PubChem CID13838

DTXSIDDTXSID2025395

FormulaC6H19NSi2

Mol. Weight161.39 g/mol

SMILESC[Si](C)(C)N[Si](C)(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID2025395Retrieved 2026-04-06
PubChem · compound 13838Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Hexamethyldisilazane (CAS 999-97-3) https://chemicalindependence.com/chemical/999-97-3/ EPA CompTox (DSSTox): DTXSID2025395. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2025395 PubChem: 13838. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/13838 EPA Chemical Data Reporting: 999-97-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 999-97-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293190 for CAS 999-97-3. Reporting year: 2024. https://usatrade.census.gov/