Fentanyl citrate

Drug ingredientActive Shortage

CAS 990-73-8

This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.

US productionNot reported

Import value, 2024$2M

Top sourceSwitzerland 86%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293333 · basket

These shares come from HS customs code 293333, which covers 11 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 86%SwitzerlandCN 11%ChinaIT 1%ItalyUA 1%Ukraine

India
Brazil
Latvia

17 FDA-registered drug labelers

Bond Pharmacy INC

Cambrex Charles City, Inc

Chattem Chemicals, Inc.

Civica, Inc.

Fresenius Kabi USA, LLC

Hikma Pharmaceuticals USA Inc.

Hospira, Inc.

LETCO MEDICAL, LLC

Medisca Inc.

Pharma Source Direct, Inc.

Phlow Corp.

Professional Compounding Centers of America dba PCCA

Siegfried Grafton, Inc.

SpecGx LLC

Spectrum Chemical and Laboratory Products

Teva Pharmaceuticals USA, Inc.

Veranova, L.P.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Fentanyl Citrate

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

Active Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

Current shortage
Fentanyl Citrate Injection
Shortage listed since January 1, 2012
Manufacturer reports: 2 unavailable, 1 limited, 2 available

See all current drug shortages

Chemical Identity

CAS990-73-8

PubChem CID13810

DTXSIDDTXSID80243933

FormulaC28H36N2O8

Mol. Weight528.6 g/mol

SMILESCCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Data Sources

PubChem · compound 13810Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Fentanyl citrate (CAS 990-73-8) https://chemicalindependence.com/chemical/990-73-8/ PubChem: 13810. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/13810 FDA National Drug Code directory: CAS 990-73-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 990-73-8. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293333 for CAS 990-73-8. Reporting year: 2024. https://usatrade.census.gov/