4-Hydroxybenzoic acid

Drug ingredient

CAS 99-96-7

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$122M

Top sourceSouth Korea 39%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291829 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291829, which covers 85 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

KR 39%South KoreaCN 26%ChinaTW 11%TaiwanJP 9%JapanSG 5%Singapore

United Kingdom
Germany
Malaysia
Mexico
Ireland
Ukraine
Slovakia
Hungary
Spain

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Aceto Us

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Syensqo Sa · BE Belgium

Solvay

2 FDA-registered drug labelers

DARMERICA, LLC

Qingdao Biopeptek Co., Ltd.

Why It Matters

Sectors

HealthAgricultureMetals & MiningPlastics & RubberCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 4 sectors as 3 functional roles.

•Corrosion inhibitor in All Other Chemical Product and Preparation Manufacturing (100%)Processing as a reactant
•Monomers in Plastics Material and Resin Manufacturing (100%)Processing as a reactant
•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (5%)Processing—incorporation into formulation, mixture, or reaction product
•Monomers in All Other Basic Organic Chemical Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.01/gAaron Chemicals LLC

CountryHong Kong

Pack$5.00 / 500 g

Purity99%

Vendors31 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

30 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.02	500 g	99%
AA BLOCKS	United States	$0.02	1 kg	98%
A2B Chem LLC	United States	$0.02	1 kg	98%
Ambeed, Inc.	United States	$0.04	1 kg	98%
Chemscene	United States	$0.06	1 kg	—
Fluorochem EU	Germany	$0.07	500 g	98%
Fluorochem UK	United Kingdom	$0.07	500 g	98%
AstaTech, Inc	United States	$0.08	250 g	95%
ALFA AESAR	Germany	$0.08	1 kg	99%
Sigma-Aldrich (Rush Stock)	Germany	$0.10	1 kg	99%
Sigma-Aldrich	Germany	$0.10	1 kg	99%
AK Scientific Specialized	United States	$0.10	1 kg	98%
AK Scientific, Inc.	United States	$0.14	1 kg	99%
Cayman Europe	Estonia	$0.19	250 g	98%
MedChemExpress MCE	Sweden	$0.23	1 kg	99.98%
Combi-Blocks, Inc.	United States	$0.25	1 kg	99%
Angene International Limited	United States	$0.32	500 g	99%
Aldlab	United States	$0.83	25 g	95%
Interbioscreen	Hong Kong	$10.00	10 g	95%
Specs	Netherlands	$132.13	10 g	90%
ChemNorm	China	$150.00	100 mg	99%
Labotest KG	Germany	$217.80	5000 mg	90%
Otava, Ltd.	Ukraine	$460.00	250 mg	90%
ChemFaces	China	$1500.00	20 mg	98%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Vitas M Chemical Limited	Hong Kong	$3170.00	100 mg	90%
Princeton BioMolecular Research (SC)	United States	$4200.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	99%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	95%
AnalytiCon Discovery - a Division of BRAIN Biotech AG	Germany	$73652.70	100 mg	85%

Chemical Identity

CAS99-96-7

PubChem CID135

DTXSIDDTXSID3026647

FormulaC7H6O3

Mol. Weight138.12 g/mol

SMILESC1=CC(=CC=C1C(=O)O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID3026647Retrieved 2026-04-06
PubChem · compound 135Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

4-Hydroxybenzoic acid (CAS 99-96-7) https://chemicalindependence.com/chemical/99-96-7/ EPA CompTox (DSSTox): DTXSID3026647. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3026647 PubChem: 135. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/135 EPA Chemical Data Reporting: 99-96-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 99-96-7. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291829 for CAS 99-96-7. Reporting year: 2024. https://usatrade.census.gov/