Allantoin

Drug ingredient

CAS 97-59-6

EPA’s 2023 records show zero U.S. production for this drug ingredient.

Molecular structure of 97-59-6
US productionZero
Import value, 2024$19M
Import volumeCBI
Top sourceChina 55%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293321 · basket

EPA reports by year
2023
US production Zero · Imports Confidential
2019
US production Not published · Imports Not published

These shares come from HS customs code 293321, which covers 22 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 55%ChinaTW 34%TaiwanIL 3%IsraelES 2%SpainIN 1%India
71 FDA-registered drug labelers
ACE PHARMACEUTICAL CO.,LTD.
Advaccine Biopharmaceuticals Suzhou Co., Ltd
Aidance Scientific, Inc, DBA Aidance Skincare & Topical Solutions
Anjon Biologics, Inc
ANUBIS COSMETICS SL
Asclemed USA, Inc.
Beijing JUNGE Technology Co., Ltd.
BENLONG HALL LLC
BESTVALUE Co., Ltd
bluemercury
Bluemercury Inc.
BR PHARM CO. , Ltd.
Carolina Cannabis Creations L.L.C
CDMA
Church & Dwight Co., Inc.
Compania Internacional de Comercio, S.A.P.I de C.V.
Cosco International, Inc.
CVS Health
Derma Care Research Labs, LLC
DLC Laboratories, Inc.
Dolgencorp Inc
Earthmed LLC
First Honey LLC
Focus Consumer Healthcare, LLC
Galderma Laboratories, L.P.
Genuine Virgin Aloe Corporation
Genujine Virgin Aloe Corporation
Guangdong Bisutang Biotechnology Co., LTD
Guangdong Youbaijia Cosmetic Industry Co., Ltd
Guangzhou Ariel Biotech Co., Ltd.
HANSCOS Co.,Ltd.
HRA PHARMA AMERICA, INC.
Hunan Jiudian Pharmaceutical Co.,Ltd.
ISP Sutton Laboratories
June Jacobs Labs LLC
KMPHARMACEUTICAL CO.,LTD
L'Oreal USA Products Inc
LAON COMMERCE co ltd
Lidan, inc.
Longway Technology(Guangzhou) Co., Ltd
MEDICELL BIO CO., Ltd.
Meijer
Neat Feat Products Limited
Noon Aesthetics M.R. Ltd
OL PHARMA TECH, LLC Drs PHARMACY
Olakino Therapeutics LLC
PARMA KOREA
PEER PHARM LTD.
Pioom Cosmetic Co.,ltd
Private Label Beauty and Wellness
PureTek Corporation
Quantum, Inc
Reedfresh Co., LTD
RENU LABORATORIES, LLC
Rite Aid
Rodan & Fields
SALICYLATES & CHEMICALS PRIVATE LIMITED
Shanghai Liangliang Bio Technology Co., Ltd
Sheffield Pharmaceuticals LLC
SHENZHEN BENLIJU BIO-TECH CO.,LTD
Skinfix, Inc.
Spectrum Laboratory Products, Inc.
TAGRID LLC
Target Corporation
The Gorilla Glue Company/O'Keeffe's Company
The Honest Company, Inc
WALGREEN COMPANY
Walgreens Company
WalMart
Yantai Aien Biotechnology Co., Ltd.
Yunqi Cosmetics (Shenzhen) Co., Ltd

Why It Matters

Sectors
Health
Downstream Uses

Appears in 117 drug and cosmetic product listings (FDA).

  • •Herpecin Pain Relief
  • •Mederma Advanced Scar
  • •AN12 ANUS Premium Cleanser
  • •Bath Bomb 2-pack (Lavender)
  • •Bath Bomb 6-pack (Lemon)
  • •Bath Bomb 6-pack (Orange)
  • •Anubismed
  • •Kenkoderm Eczema Honey Intensive Soothing Balm
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.02/gAaron Chemicals LLC
CountryHong Kong
Pack$12.00 / 500 g
Purity98%
Vendors32 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS97-59-6
PubChem CID204
DTXSIDDTXSID3020043
FormulaC4H6N4O3
Mol. Weight158.12 g/mol
SMILESC1(C(=O)NC(=O)N1)NC(=O)N

Data Sources

Brief citations

Allantoin (CAS 97-59-6) https://chemicalindependence.com/chemical/97-59-6/ EPA CompTox (DSSTox): DTXSID3020043. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3020043 PubChem: 204. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/204 EPA Chemical Data Reporting: 97-59-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 97-59-6. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293321 for CAS 97-59-6. Reporting year: 2024. https://usatrade.census.gov/