apalutamide

Drug ingredient

CAS 956104-40-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 956104-40-8
US productionNot reported
Import value, 2024$7.4B
Top sourceJapan 28%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339, 382499 · basket

These shares come from HS customs code 293339, 382499, which covers 602 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
JP 28%JapanKR 23%South KoreaCN 9%ChinaDE 8%GermanyCA 5%Canada
11 FDA-registered drug labelers
Aurobindo Pharma Limited
Catalent Pharma Solutions LLC
Dr. Reddy's Laboratories Limited
HETERO LABS LIMITED
HOVIONE FARMACIENCIA SA
Janssen Ortho LLC
Janssen Pharmaceutica NV
Janssen Pharmaceutical Sciences Unlimited Company
Janssen Products, LP
Laurus Labs Limited
MSN Laboratories Private Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Erleada
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$35.52/gA2B Chem LLC
CountryUnited States
Pack$888.00 / 25 g
Purity95%
Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS956104-40-8
PubChem CID24872560
DTXSIDDTXSID40241899
FormulaC21H15F4N5O2S
Mol. Weight477.4 g/mol
SMILESCNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F)F

Data Sources

Brief citations

apalutamide (CAS 956104-40-8) https://chemicalindependence.com/chemical/956104-40-8/ PubChem: 24872560. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/24872560 FDA National Drug Code directory: CAS 956104-40-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339,382499 for CAS 956104-40-8. Reporting year: 2024. https://usatrade.census.gov/