Salmeterol xinafoate

Drug ingredient

CAS 94749-08-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 94749-08-3
US productionNot reported
Import value, 2024$652M
Top sourceSingapore 77%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292250 · basket

These shares come from HS customs code 292250, which covers 76 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 77%SingaporeCN 12%ChinaIT 4%ItalyIN 2%IndiaGB 1%United Kingdom
25 FDA-registered drug labelers
A-S Medication Solutions
Aarti Pharmalabs Limited
Amphastar Nanjing Pharmaceuticals
Bryant Ranch Prepack
Cipla Ltd.
Glaxo Wellcome Manufacturing Pte. Ltd
GlaxoSmithKline LLC
Hikma Pharmaceuticals USA Inc.
Hovione FarmaCiencia SA
Hovione PharmaScience Limited
Industriale Chimica
Industriale Chimica s.r.l.
Inke SA
Lannett Company, Inc.
Melody Healthcare Pvt. Ltd.
MSN Laboratories Private Limited
Mylan Pharmaceuticals Inc.
Natco Pharma Limited
Neuland Laboratories Limited
Prasco Laboratories
Preferred Pharmaceuticals Inc.
Proficient Rx LP
REMEDYREPACK INC.
Teva Pharmaceuticals USA, Inc.
Teva Respiratory, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

  • •Fluticasone Propionate and Salmeterol
  • •Advair Diskus
  • •AirDuo RespiClick
  • •Wixela Inhub
  • •Advair HFA
  • •Fluticasone Propionate and Salmeterol Diskus
  • •Fluticasone Propionate and Salmeterol HFA
  • •Serevent Diskus
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Fluticasone Propionate; Salmeterol Xinafoate Powder

    Shortage listed since June 13, 2025

See all current drug shortages

Vendor Pricing

$300.00/gCombi-Blocks, Inc.
CountryUnited States
Pack$300.00 / 1 g
Purity98%
Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS94749-08-3
PubChem CID56801
DTXSIDDTXSID1045798
FormulaC36H45NO7
Mol. Weight603.7 g/mol
SMILESC1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O.C1=CC=C2C(=C1)C=CC(=C2O)C(=O)O

Data Sources

Brief citations

Salmeterol xinafoate (CAS 94749-08-3) https://chemicalindependence.com/chemical/94749-08-3/ PubChem: 56801. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/56801 FDA National Drug Code directory: CAS 94749-08-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 94749-08-3. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 292250 for CAS 94749-08-3. Reporting year: 2024. https://usatrade.census.gov/