Tucatinib

Drug ingredient

CAS 937263-43-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 937263-43-9
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
5 FDA-registered drug labelers
Catalent Pharma Solutions, LLC
Corden Pharma GmbH
Esteve Quimica SA
HOVIONE FARMACIENCIA SA
SEAGEN INC.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Tukysa
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$80.80/gAaron Chemicals LLC
CountryHong Kong
Pack$404.00 / 5 g
Purity98%
Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS937263-43-9
PubChem CID51039094
DTXSIDDTXSID601027958
FormulaC26H24N8O2
Mol. Weight480.5 g/mol
SMILESCC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5

Data Sources

Brief citations

Tucatinib (CAS 937263-43-9) https://chemicalindependence.com/chemical/937263-43-9/ PubChem: 51039094. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/51039094 FDA National Drug Code directory: CAS 937263-43-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 937263-43-9. Reporting year: 2024. https://usatrade.census.gov/