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Setmelanotide

Drug ingredient

CAS 920014-72-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 920014-72-8
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
1 FDA-registered drug labeler
Rhythm Pharmaceuticals, Inc

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Imcivree
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS920014-72-8
PubChem CID11993702
DTXSIDDTXSID501032320
FormulaC49H68N18O9S2
Mol. Weight1117.3 g/mol
SMILESCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)N1)NC(=O)C(CCCN=C(N)N)NC(=O)C)C(=O)N)CC2=CNC3=CC=CC=C32)CCCN=C(N)N)CC4=CC=CC=C4)CC5=CN=CN5

Data Sources

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Brief citations

Setmelanotide (CAS 920014-72-8) https://chemicalindependence.com/chemical/920014-72-8/ PubChem: 11993702. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11993702 FDA National Drug Code directory: CAS 920014-72-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 920014-72-8. Reporting year: 2024. https://usatrade.census.gov/