Pilocarpine

Drug ingredient

CAS 92-13-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$171M

Top sourceSwitzerland 40%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293979 · basket

These shares come from HS customs code 293979, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 40%SwitzerlandCN 18%ChinaIT 14%ItalyDE 13%GermanyIN 10%India

Australia
Poland
Belgium
Taiwan
Canada
Japan
Spain
Mexico
New Zealand
Slovenia
Israel

1 FDA-registered drug labeler

Catalent Micron Technologies, Inc.

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Pilocarpine Hydrochloride Ophthalmic Solution
Shortage listed since March 24, 2026
to be discontinued
Pilocarpine Hydrochloride Tablet
Shortage listed since September 19, 2025

See all current drug shortages

Chemical Identity

CAS92-13-7

PubChem CID5910

DTXSIDDTXSID1021162

FormulaC11H16N2O2

Mol. Weight208.26 g/mol

SMILESCCC1C(COC1=O)CC2=CN=CN2C

Data Sources

PubChem · compound 5910Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Pilocarpine (CAS 92-13-7) https://chemicalindependence.com/chemical/92-13-7/ PubChem: 5910. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5910 EPA TSCA Inventory: CAS 92-13-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 92-13-7. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293979 for CAS 92-13-7. Reporting year: 2024. https://usatrade.census.gov/