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Coumarin

Drug ingredient

CAS 91-64-5

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 91-64-5
US productionCBI
Import value, 2024$286M
Top sourceChina 48%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293220 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293220, which covers 151 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 48%ChinaIN 15%IndiaJP 7%JapanGB 7%United KingdomCH 7%Switzerland
Domestic parents -- activity not disclosed (2)
Reckitt Benckiser
Takasago
EPA-registered importers (11)
Reckitt Benckiser Group · GB United Kingdom
Symrise Ag · DE Germany
Atotech Usa
Berje
Colgate-Palmolive
Show all 11
Givaudan Fragrances
Henkel Us Operations
International Flavors And Fragrances
S.C. Johnson & Son
Symrise
Tilley Distribution
6 FDA-registered drug labelers
ANUBIS COSMETICS SL
Deseret Biologicals, Inc
Dr. Donna Restivo DC
Energetix Corporation
Energique, Inc.
Professional Complementary Health Formulas

Why It Matters

Sectors
HealthConsumer ProductsPaints & CoatingsCore Chemicals
Downstream Uses

Appears in 14 drug and cosmetic product listings (FDA).

  • •Vascuflow
  • •BP Reg
  • •Bread Cravings
  • •Anubis Barcelona Regul Oil
  • •Breathe
  • •Dairy Allergen Mix
  • •Chip Cravings
  • •Respiratory Plus
Show all 14
  • •REFL HS
  • •Isopathic Phenolic Rings
  • •Opsin I 6014
  • •Multi-Phenolic
  • •Coumarin 1513
  • •Allermilk
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 6 sectors as 2 functional roles.

  • •Fragrance in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Fragrance in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Plating agent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Fragrance in Not Known or Reasonably Ascertainable (100%)Not Known or Reasonably Ascertainable
  • •Fragrance in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Fragrance in Wholesale and Retail Trade (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.04/gAmbeed, Inc.
CountryUnited States
Pack$45.00 / 1 kg
Purity99%
Vendors28 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

27 more vendors
VendorCountry$/gPackPurity
ChemsceneUnited States$0.051 kg—
Fluorochem EUGermany$0.11100 g95%
AK Scientific SpecializedUnited States$0.14500 g98%
AK Scientific, Inc.United States$0.18500 g99%
Fluorochem UKUnited Kingdom$0.3425 g95%
Combi-Blocks, Inc.United States$0.40500 g98%
Sigma-Aldrich (Rush Stock)Germany$0.55500 g99%
Sigma-AldrichGermany$0.55500 g99%
AstaTech (2 weeks)United States$1.17100 g95%
MedChemExpress MCESweden$22.515 g99.81%
ChemDiv, Inc.United States$25.0025 g90%
InterbioscreenHong Kong$34.0010 g95%
TargetMol ChemicalsChina → United States$38.001 g99.96%
TargetMol Chemicals EUAustria$62.00500 mg99.96%
Chengdu Biopurify Phytochemicals Ltd.China$142.001 g98%
Labotest KGGermany$217.805000 mg90%
MolnovaChina$600.0050 mg99%
ChemNormChina$600.0020 mg98%
Apexbio Technology LLCUnited States$1400.0050 mg99.84%
ChemFacesChina$1500.0020 mg98%
Otava, Ltd.Ukraine$2280.0050 mg95%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg95%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
Vitas M Chemical LimitedHong Kong$3170.00100 mg90%
SpecsNetherlands$5674.90100 mg90%
Key Organics Ltd.United Kingdom$6900.0010 mg95%
AnalytiCon Discovery - a Division of BRAIN Biotech AGGermany$73652.70100 mg85%

Chemical Identity

CAS91-64-5
PubChem CID323
DTXSIDDTXSID7020348
FormulaC9H6O2
Mol. Weight146.14 g/mol
SMILESC1=CC=C2C(=C1)C=CC(=O)O2

Data Sources

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Brief citations

Coumarin (CAS 91-64-5) https://chemicalindependence.com/chemical/91-64-5/ EPA CompTox (DSSTox): DTXSID7020348. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7020348 PubChem: 323. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/323 EPA Chemical Data Reporting: 91-64-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 91-64-5. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293220 for CAS 91-64-5. Reporting year: 2024. https://usatrade.census.gov/