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Heparin sodium

Drug ingredientActive Shortage

CAS 9041-08-1

This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.

Molecular structure of 9041-08-1
1 Na⁺
US productionNot reported
Import value, 2024$426M
Top sourceChina 36%

EPA exempts this chemical from its production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 300190 · narrow

These shares come from HS customs code 300190, which covers 2 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 36%ChinaDE 14%GermanyIN 13%IndiaNZ 8%New ZealandSG 4%Singapore
49 FDA-registered drug labelers
Amphastar Nanjing Pharmaceuticals, Inc.
ANIMEX FOODS SP Z O O ODDZIAL W STARACHOWICACH
Aspen Oss B.V.
B. Braun Medical Inc.
Baxter Healthcare Corporation
BE Pharmaceuticals Inc.
BioChem Oss
Biofer, SpA
Bioiberica SAU
Biopharmacotech Sp z o o Spolka Komandytowa
Canada Packers Inc.
Cardinal Health 107, LLC
CHANGZHOU QIANHONG BIO PHARMA CO LTD
Civica, Inc.
DARMERICA, LLC
Fresenius Kabi USA, LLC
Gland Pharma Limited
Haotai Health Jisheng (Jilin) Biotechnology Co., Ltd.
Hebei Changshan Biochemical Pharmaceutical Co., Ltd.
Henry Schein, Inc.
Hepac B.V.
Hepalink USA Inc.
HF Acquisition Co LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
Hospira, Inc.
Hubei Enoray Biopharmaceutical Co., Ltd.
Luohe Huisheng Bio-tech Co.,Ltd.
McKesson Corporation dba SKY Packaging
Medical Purchasing Solutions, LLC
Meitheal Pharmaceuticals Inc.
Mobren Transport, Inc.
Mylan Institutional LLC
Nanjing King-Friend Biochemical Pharmaceutical Co., Ltd
NorthStar RxLLC
Olymel
Pfizer Laboratories Div Pfizer Inc
Pharmacia Hepar LLC
Phlow Corporation
Plano Pharmaceuticals Inc.
Professional Compounding Centers of America
Qingdao Jiulong Biopharmaceutical Co., Ltd.
REMEDYREPACK INC.
Sagent Pharmaceticals
Sagent Pharmaceuticals
Sandoz Inc.
Scientific Protein Laboratories LLC
Shenzhen Hepalink Pharmaceutical Group Co.,Ltd.
Smithfield Bioscience, Inc.
Yantai Dongcheng Biochemicals Co.,Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

  • •Heparin Sodium
  • •Heparin Sodium and Dextrose
  • •Heparin Sodium in Dextrose
  • •Heparin Sodium in Sodium Chloride
FDA Shortage Status
Active Shortage
Shortage History
  • Current shortage

    Heparin Sodium Injection

    Shortage listed since November 14, 2017

    Manufacturer reports: 1 unavailable, 1 limited, 1 available

See all current drug shortages

Chemical Identity

CAS9041-08-1
PubChem CID92044406
DTXSIDDTXSID301010914
FormulaC26H42N2NaO37S5+
Mol. Weight1157.9 g/mol
SMILESCC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O.[Na+]

Data Sources

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Brief citations

Heparin sodium (CAS 9041-08-1) https://chemicalindependence.com/chemical/9041-08-1/ PubChem: 92044406. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/92044406 EPA TSCA Inventory: CAS 9041-08-1. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 9041-08-1. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 300190 for CAS 9041-08-1. Reporting year: 2024. https://usatrade.census.gov/