Polysorbate 20

Drug ingredient

CAS 9005-64-5

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$218M

Top sourceGermany 21%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 340242 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Zero · Imports Zero

These shares come from HS customs code 340242, which covers 45 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 21%GermanyKR 11%South KoreaIT 10%ItalyCA 9%CanadaMX 8%Mexico

Austria
Brazil
Slovakia
Egypt
Uruguay
Australia
Taiwan
Malaysia
Indonesia
Czech Republic
Israel
Philippines
Colombia
Argentina
Ireland
Portugal
Finland
Costa Rica
Vietnam
Dominican Republic
El Salvador
Bulgaria
Peru

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Givaudan Fragrances

2 FDA-registered drug labelers

ANUBIS COSMETICS SL

Fagron Inc

Why It Matters

Sectors

HealthCore Chemicals

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Anubis Barcelona
•Anubis Barcelona Total Hydrating

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 1 sector as 2 functional roles.

•Fixing agent (mordant) in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Fragrance in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS9005-64-5

PubChem CIDNot recorded

DTXSIDDTXSID3031949

FormulaNot recorded

Mol. WeightNot recorded

SMILESNot recorded

Data Sources

EPA CompTox (DSSTox) · DTXSID3031949Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Polysorbate 20 (CAS 9005-64-5) https://chemicalindependence.com/chemical/9005-64-5/ EPA CompTox (DSSTox): DTXSID3031949. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3031949 EPA Chemical Data Reporting: 9005-64-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 9005-64-5. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 340242 for CAS 9005-64-5. Reporting year: 2024. https://usatrade.census.gov/