Toremifene citrate

Drug ingredient

CAS 89778-27-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$197M

Top sourceChina 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292219 · basket

These shares come from HS customs code 292219, which covers 167 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 36%ChinaIT 15%ItalyDE 14%GermanyIN 7%IndiaHU 5%Hungary

Saudi Arabia
Lithuania
Canada
Ukraine
Israel
Singapore
Mexico
Ireland
Netherlands
Malaysia
Slovakia
Denmark
Finland
Latvia
Greece
Austria

7 FDA-registered drug labelers

AX Pharmaceutical Corp

Kyowa Kirin, Inc.

MSN Laboratories Private Limited

Novadoz Pharmaceuticals LLC

Orion Corporation, Orion Pharma

QINGDAO TIDA BIOTEK CO.,LTD

Rising Pharma Holdings, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Fareston
•toremifene citrate

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS89778-27-8

PubChem CID3005572

DTXSIDDTXSID2021367

FormulaC32H36ClNO8

Mol. Weight598.1 g/mol

SMILESCN(C)CCOC1=CC=C(C=C1)C(=C(CCCl)C2=CC=CC=C2)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Data Sources

PubChem · compound 3005572Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Toremifene citrate (CAS 89778-27-8) https://chemicalindependence.com/chemical/89778-27-8/ PubChem: 3005572. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3005572 FDA National Drug Code directory: CAS 89778-27-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292219 for CAS 89778-27-8. Reporting year: 2024. https://usatrade.census.gov/