Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one-6'-(dibutylamino)-3'-methyl-2'-(phenylamino)-

CAS 89331-94-2

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$286M

Top sourceChina 48%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293220 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293220, which covers 151 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 48%ChinaIN 15%IndiaJP 7%JapanGB 7%United KingdomCH 7%Switzerland

Mexico
Austria
Indonesia
Czech Republic
Slovakia
Malaysia
Israel
Poland
Vietnam
Ukraine
South Africa
Singapore
Russia
Lithuania
Hungary
Belarus
Brazil
Australia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Sofix

Domestic parents -- activity not disclosed (2)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Marubeni America

Pixelle Specialty Solutions

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Connect Chemicals Usa

Ricoh Electronics

Why It Matters

Sectors

TextilesPaper & Printing

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 1 functional role.

•Dye in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant
•Dye in Paper Manufacturing (100%)Processing—incorporation into article

Vendor Pricing

$0.63/gCombi-Blocks, Inc.

CountryUnited States

Pack$315.00 / 500 g

Purity98%

Vendors23 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

22 more vendors

Vendor	Country	$/g	Pack	Purity
Chemscene	United States	$0.72	500 g	—
BLD Pharmatech Co., Limited	United States	$0.72	500 g	97%
BLD Pharmatech GmbH	Germany	$0.72	500 g	97%
BLD Pharmatech Ltd.	China	$0.72	500 g	97%
Ambeed, Inc.	United States	$0.72	500 g	97%
A2B Chem LLC	United States	$0.77	500 g	98%
AA BLOCKS	United States	$0.81	500 g	95%
Aaron Chemicals LLC	Hong Kong	$0.90	500 g	98%
MedChemExpress MCE	Sweden	$0.90	500 g	—
Angene Chemical	China → Hong Kong	$0.96	500 g	98%
AK Scientific Specialized	United States	$1.20	100 g	95%
AK Scientific, Inc.	United States	$1.61	100 g	98%
Fluorochem EU	Germany	$1.98	25 g	98%
Synthonix	United States	$5.00	5 g	97%
AstaTech (2 weeks)	United States	$5.40	100 g	95%
Angene International Limited	United States	$21.00	1 g	95%
ChemDiv, Inc.	United States	$4070.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Princeton BioMolecular Research (SC)	United States	$5000.00	30 mg	90%
Vitas M Chemical Limited	Hong Kong	$5133.33	30 mg	90%
Interbioscreen	Hong Kong	$6072.00	100 mg	95%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS89331-94-2

PubChem CID3534526

DTXSIDDTXSID3029817

FormulaC35H36N2O3

Mol. Weight532.7 g/mol

SMILESCCCCN(CCCC)C1=CC2=C(C=C1)C3(C4=CC=CC=C4C(=O)O3)C5=C(O2)C=C(C(=C5)NC6=CC=CC=C6)C

Data Sources

EPA CompTox (DSSTox) · DTXSID3029817Retrieved 2026-04-06
PubChem · compound 3534526Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one-6'-(dibutylamino)-3'-methyl-2'-(phenylamino)- (CAS 89331-94-2) https://chemicalindependence.com/chemical/89331-94-2/ EPA CompTox (DSSTox): DTXSID3029817. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3029817 PubChem: 3534526. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/3534526 EPA Chemical Data Reporting: 89331-94-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 89331-94-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293220 for CAS 89331-94-2. Reporting year: 2024. https://usatrade.census.gov/