2-Amino-5-chloro-4-methylbenzenesulfonic acid

CAS 88-53-9

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$59M

Import volumeZero

Top sourceGermany 55%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292143 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292143, which covers 45 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 55%GermanyIT 30%ItalyIN 11%IndiaJP 2%JapanCN 1%China

South Korea
United Kingdom
Taiwan

Why It Matters

Sectors

Textiles

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Pigment in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.06/gA2B Chem LLC

CountryUnited States

Pack$32.00 / 500 g

Purity98%

Vendors9 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

8 more vendors

Vendor	Country	$/g	Pack	Purity
Combi-Blocks, Inc.	United States	$0.25	1 kg	98%
AA BLOCKS	United States	$0.28	1 kg	98%
AK Scientific Specialized	United States	$0.41	100 g	95%
AK Scientific, Inc.	United States	$0.57	100 g	98%
Aaron Chemicals LLC	Hong Kong	$0.80	25 g	98%
Angene Chemical	China → Hong Kong	$0.88	25 g	98%
Angene International Limited	United States	$1.23	100 g	98%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS88-53-9

PubChem CID6936

DTXSIDDTXSID7026528

FormulaC7H8ClNO3S

Mol. Weight221.66 g/mol

SMILESCC1=CC(=C(C=C1Cl)S(=O)(=O)O)N

Data Sources

EPA CompTox (DSSTox) · DTXSID7026528Retrieved 2026-04-06
PubChem · compound 6936Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2-Amino-5-chloro-4-methylbenzenesulfonic acid (CAS 88-53-9) https://chemicalindependence.com/chemical/88-53-9/ EPA CompTox (DSSTox): DTXSID7026528. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7026528 PubChem: 6936. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6936 EPA Chemical Data Reporting: 88-53-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 88-53-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292143 for CAS 88-53-9. Reporting year: 2024. https://usatrade.census.gov/