2,6-Di-tert-butyl-4-[(dimethylamino)methyl]phenol

CAS 88-27-7

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$64M

Top sourceChina 52%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292229 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292229, which covers 84 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 52%ChinaJP 25%JapanIN 18%IndiaIT 3%ItalyKR 1%South Korea

United Kingdom
Ukraine
Canada
Switzerland
Ireland
Netherlands
Israel
Singapore
Latvia
Hong Kong
Belgium

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Pmc Global

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Quaker Houghton

Resin Solutions

Why It Matters

Sectors

EnergyPlastics & Rubber

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•Lubricating agent in Petroleum Lubricating Oil and Grease Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Heat stabilizer in Rubber Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.01/gAaron Chemicals LLC

CountryHong Kong

Pack$5.00 / 500 g

Purity98%

Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

18 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.01	500 g	98%
A2B Chem LLC	United States	$0.03	500 g	98%
BLD Pharmatech GmbH	Germany	$0.03	1 kg	98%
BLD Pharmatech Ltd.	China	$0.03	1 kg	98%
AA BLOCKS	United States	$0.03	500 g	98%
BLD Pharmatech Co., Limited	United States	$0.11	1 kg	98%
Ambeed, Inc.	United States	$0.11	1 kg	98%
Fluorochem UK	United Kingdom	$0.14	50 g	95%
Combi-Blocks, Inc.	United States	$0.25	1 kg	98%
Sigma-Aldrich (Rush Stock)	Germany	$0.34	1 kg	96%
Sigma-Aldrich	Germany	$0.34	1 kg	96%
AK Scientific, Inc.	United States	$0.45	100 g	98%
AstaTech (2 weeks)	United States	$0.46	500 g	95%
Angene International Limited	United States	$1.05	100 g	98%
Labotest KG	Germany	$453.00	1000 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
TimTec, LLC	United States	$13333.33	30 mg	90%
ChemBridge Corporation	Kazakhstan	$62000.00	1 mg	90%

Chemical Identity

CAS88-27-7

PubChem CID66609

DTXSIDDTXSID0044997

FormulaC17H29NO

Mol. Weight263.4 g/mol

SMILESCC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CN(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID0044997Retrieved 2026-04-06
PubChem · compound 66609Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2,6-Di-tert-butyl-4-[(dimethylamino)methyl]phenol (CAS 88-27-7) https://chemicalindependence.com/chemical/88-27-7/ EPA CompTox (DSSTox): DTXSID0044997. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0044997 PubChem: 66609. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/66609 EPA Chemical Data Reporting: 88-27-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 88-27-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292229 for CAS 88-27-7. Reporting year: 2024. https://usatrade.census.gov/