N-Methyl-2-pyrrolidone
CAS 872-50-4
U.S. production volumes are classified as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$171M
Top sourceSwitzerland 40%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293979 · basket
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 293979, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CH 40%SwitzerlandCN 18%ChinaIT 14%ItalyDE 13%GermanyIN 10%India
- Australia
- Poland
- Belgium
- Taiwan
- Canada
- Japan
- Spain
- Mexico
- New Zealand
- Slovenia
- Israel
EPA-registered manufacturers (6)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Ashland
Basf
Eden Custom Processing
Lyondell Chemical
Show all 6
Macdermid
Domestic parents -- activity not disclosed (15)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
A.G. Layne
Ambyth Chemical
American River Brokerage
Brenntag
Cellmark Basic Materials
Show all 15
Daxx
Emd Holding
Ideal Chemical & Supply
Koch Industries
Lg Energy Solution Michigan
Polyventive
Sk Battery America
Tedia
Toyo Ink International
Transchem
EPA-registered importers (15)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Shin-Etsu Chemical · JP Japan
Sumitomo Chemical · JP Japan
Allchem Industries Holding
American Vanguard
Show all 15
Doremus Terminal
Elantas Pdg
Greenchem Industries
Hubbard-Hall
Mak Chemicals
Shintech Louisiana
Stahl Usa
Sumitomo Chemical Advanced Technologies
Ultium Cells Holdings
Wego Chemical Group
Why It Matters
Sectors
HealthAgricultureEnergyElectronicsTransportationMetals & MiningPlastics & RubberTextilesConsumer ProductsPaints & CoatingsCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 18 sectors as 12 functional roles.
- •Solvent in Pharmaceutical and Medicine Manufacturing (80%)Processing—repackaging
- •Polymerization promoter in All Other Basic Organic Chemical Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in All Other Basic Organic Chemical Manufacturing (100%)Use—non-incorporative activities
- •Solvent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (8%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Paint and Coating Manufacturing (5%)Processing as a reactant
- •Solvent in Electrical Equipment, Appliance, and Component Manufacturing (21%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Wholesale and Retail Trade (32%)Processing—repackaging
- •Solvent in Paint and Coating Manufacturing (34%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Computer and Electronic Product Manufacturing (100%)Use—non-incorporative activities
- •Solvent in Not Known or Reasonably Ascertainable (100%)Processing—incorporation into article
- •Solvent in Transportation Equipment ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Solvent in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Computer and Electronic Product ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Diluent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Pharmaceutical and Medicine ManufacturingProcessing as a reactant
- •Intermediate in Plastics Material and Resin ManufacturingProcessing as a reactant
- •Processing aids, specific to petroleum production in Petrochemical ManufacturingUse—non-incorporative activities
- •Intermediate in Wholesale and Retail TradeProcessing—repackaging
- •Solvent in Soap, Cleaning Compound, and Toilet Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into article
- •Laboratory chemicals in Wholesale and Retail TradeNot Known or Reasonably Ascertainable
- •Laboratory chemicals in ServicesNot Known or Reasonably Ascertainable
- •Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
- •Cleaning agent in Fabricated Metal Product ManufacturingUse—non-incorporative activities
- •Pigment in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Agriculture, Forestry, Fishing and Hunting (15%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Agriculture, Forestry, Fishing and Hunting (0%)Processing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.03/gA2B Chem LLC (2 weeks)
CountryUnited States
Pack$67.00 / 2.5 kg
Purity98%
Vendors20 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
19 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| AA BLOCKS (2 weeks) | United States | $0.03 | 2.5 kg | 98% |
| A2B Chem LLC | United States | $0.05 | 1 kg | 99% |
| Aaron Chemicals LLC | Hong Kong | $0.06 | 100 g | 98% |
| AA BLOCKS | United States | $0.06 | 1 kg | 99% |
| Chemscene | United States | $0.07 | 1 kg | — |
| Fluorochem UK | United Kingdom | $0.08 | 1 kg | 99% |
| Angene Chemical | China → Hong Kong | $0.08 | 100 g | 98% |
| Fluorochem EU | Germany | $0.09 | 500 g | 99% |
| MedChemExpress MCE | Sweden | $0.21 | 1 kg | 99.99% |
| AstaTech, Inc | United States | $0.59 | 500 g | 95% |
| Interbioscreen | Hong Kong | $24.00 | 10 g | 95% |
| Sigma-Aldrich (Rush Stock) | Germany | $71.96 | 2 g | — |
| Sigma-Aldrich | Germany | $71.96 | 2 g | — |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
| Otava, Ltd. | Ukraine | $2280.00 | 50 mg | 95% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 90% |
| Princeton BioMolecular Research (SC) | United States | $2900.00 | 100 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
| TimTec, LLC | United States | $9333.33 | 30 mg | 99.5% |
Chemical Identity
CAS872-50-4
PubChem CID13387
DTXSIDDTXSID6020856
FormulaC5H9NO
Mol. Weight99.13 g/mol
SMILESCN1CCCC1=O
Data Sources
- EPA CompTox (DSSTox) · DTXSID6020856Retrieved 2026-04-06
- PubChem · compound 13387Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
N-Methyl-2-pyrrolidone (CAS 872-50-4) https://chemicalindependence.com/chemical/872-50-4/ EPA CompTox (DSSTox): DTXSID6020856. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6020856 PubChem: 13387. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/13387 EPA Chemical Data Reporting: 872-50-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 872-50-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293979 for CAS 872-50-4. Reporting year: 2024. https://usatrade.census.gov/