(-)-(E)-Caryophyllene

CAS 87-44-5

Companies reported imports and no US production of this chemical to EPA for 2023.

US productionZero

Import value, 2024$90M

Import volume93.5K lb

Import dependency100%

Top sourceJapan 21%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

(-)-(E)-Caryophyllene · US import value by year

2013: $75M · Peak 2018: $116M · 2024: $90M · 2025: $77M

Where It Comes From

Customs basis: HS 290219 · basket

EPA reports by year

2023: US production Zero · Imports 93.5K lb
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290219, which covers 108 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

JP 21%JapanBR 12%BrazilTW 12%TaiwanKR 11%South KoreaDE 9%Germany

Russia
United Kingdom
Indonesia
South Africa
Ukraine
Madagascar
Hungary
Hong Kong
Czech Republic
Israel

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Reckitt Benckiser

EPA-registered importers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Reckitt Benckiser Group · GB United Kingdom

Berje

Brenntag

Henkel Us Operations

Why It Matters

Sectors

Consumer Products

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 1 functional role.

•Fragrance in Not Known or Reasonably Ascertainable (100%)Not Known or Reasonably Ascertainable
•Fragrance in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$74.00/gMolnova

CountryChina

Pack$37.00 / 500 mg

Purity99%

Vendors1 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS87-44-5

PubChem CID5281515

DTXSIDDTXSID8024739

FormulaC15H24

Mol. Weight204.35 g/mol

SMILESCC1=CCCC(=C)C2CC(C2CC1)(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID8024739Retrieved 2026-04-06
PubChem · compound 5281515Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

(-)-(E)-Caryophyllene (CAS 87-44-5) https://chemicalindependence.com/chemical/87-44-5/ EPA CompTox (DSSTox): DTXSID8024739. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8024739 PubChem: 5281515. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/5281515 EPA Chemical Data Reporting: 87-44-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 87-44-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290219 for CAS 87-44-5. Reporting year: 2024. https://usatrade.census.gov/