Fostemsavir tromethamine

Drug ingredient

CAS 864953-39-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

2 FDA-registered drug labelers

Piramal Healthcare UK Limited

ViiV Healthcare Company

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Rukobia

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$720.00/gCombi-Blocks, Inc.

CountryUnited States

Pack$720.00 / 1 g

Purity95%

Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

10 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$952.00	250 mg	98%
AA BLOCKS	United States	$1056.00	250 mg	98%
Ambeed, Inc.	United States	$1336.00	250 mg	98%
Aaron Chemicals LLC	Hong Kong	$1348.00	250 mg	98%
Angene Chemical	China → Hong Kong	$1364.00	250 mg	98%
TargetMol Chemicals	China → United States	$6450.00	100 mg	99.95%
Molnova	China	$6980.00	100 mg	99%
MedChemExpress MCE	Sweden	$9752.60	100 mg	99.78%
Angene International Limited	United States	$12810.00	100 mg	98%
AstaTech (2 weeks)	United States	$51400.00	5 mg	95%

Chemical Identity

CAS864953-39-9

PubChem CID46892186

DTXSIDDTXSID201006863

FormulaC29H37N8O11P

Mol. Weight704.6 g/mol

SMILESCC1=NN(C=N1)C2=NC=C(C3=C2N(C=C3C(=O)C(=O)N4CCN(CC4)C(=O)C5=CC=CC=C5)COP(=O)(O)O)OC.C(C(CO)(CO)N)O

Data Sources

PubChem · compound 46892186Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Fostemsavir tromethamine (CAS 864953-39-9) https://chemicalindependence.com/chemical/864953-39-9/ PubChem: 46892186. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/46892186 FDA National Drug Code directory: CAS 864953-39-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 864953-39-9. Reporting year: 2024. https://usatrade.census.gov/