Empagliflozin

Drug ingredient

CAS 864070-44-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$64M

Top sourceChina 37%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293219 · basket

These shares come from HS customs code 293219, which covers 136 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 37%ChinaIT 23%ItalyJP 20%JapanIN 12%IndiaES 2%Spain

Belgium
Germany
Netherlands
Canada
Mexico
Slovakia
Malaysia
Portugal
Taiwan
Sweden
Latvia
Israel

30 FDA-registered drug labelers

A-S Medication Solutions

Aphena Pharma Solutions - Tennessee, LLC

Aurobindo Pharma Limited

Bidachem S.p.a.

Biocon Limited

Boehringer Ingelheim Espaa, S.A.

BOEHRINGER INGELHEIM HELLAS SINGLE MEMBER S.A.

Boehringer Ingelheim Pharma GmbH and Co. KG

Boehringer Ingelheim Pharmaceuticals, Inc.

Boehringer Ingelheim Promeco S.A. de C.V.

Cardinal Health 107, LLC

Cipla Ltd.

Cohance Lifesciences Limited

Dr. Reddy's Laboratories Limited

Dr. Reddy's Laboratories Ltd.

EMNAR PHARMA PRIVATE LIMITED

Granules India Limited

Honour Lab Limited

Lee Pharma Ltd.

Macleods Pharmaceuticals Limited

Matrix Pharmacorp Private Limited

Metrochem API Private Limited

MSN Life Sciences Private Limited

Patheon Puerto Rico, Inc.

Qingdao Biopeptek Co., Ltd.

Rottendorf Pharma GmbH

SMS Pharmaceuticals Limited

SUN PHARMACEUTICAL INDUSTRIES, INC.

USV Private Limited

ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Synjardy
•Synjardy XR
•Trijardy XR
•Glyxambi
•Jardiance

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS864070-44-0

PubChem CID11949646

DTXSIDDTXSID601026093

FormulaC23H27ClO7

Mol. Weight450.9 g/mol

SMILESC1COCC1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl

Data Sources

PubChem · compound 11949646Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Empagliflozin (CAS 864070-44-0) https://chemicalindependence.com/chemical/864070-44-0/ PubChem: 11949646. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11949646 FDA National Drug Code directory: CAS 864070-44-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293219 for CAS 864070-44-0. Reporting year: 2024. https://usatrade.census.gov/