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Trofinetide

Drug ingredient

CAS 853400-76-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 853400-76-7
US productionNot reported
Import value, 2024$1.4B
Top sourceIreland 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
5 FDA-registered drug labelers
Acadia Pharmaceuticals Inc.
Biophore India Pharmaceuticals Pvt. Ltd
Corden Pharma Bergamo SpA
F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.
FLAMMA S.P.A.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Daybue Stix
  • •Daybue
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS853400-76-7
PubChem CID11318905
DTXSIDDTXSID101336041
FormulaC13H21N3O6
Mol. Weight315.32 g/mol
SMILESCC1(CCCN1C(=O)CN)C(=O)NC(CCC(=O)O)C(=O)O

Data Sources

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Brief citations

Trofinetide (CAS 853400-76-7) https://chemicalindependence.com/chemical/853400-76-7/ PubChem: 11318905. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11318905 FDA National Drug Code directory: CAS 853400-76-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 853400-76-7. Reporting year: 2024. https://usatrade.census.gov/