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Amphetamine aspartate monohydrate

Drug ingredientActive Shortage

CAS 851591-76-9

This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.

Molecular structure of 851591-76-9
1 H₂O
US productionNot reported
Import value, 2024$503M
Top sourceChina 25%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
30 FDA-registered drug labelers
Actavis Pharma, Inc.
Alvogen Inc.
Amneal Pharmaceuticals of New York LLC
Aurolife Pharma, LLC
Bryant Ranch Prepack
Burel Pharmaceuticals, LLC
Camber Pharmaceuticals, Inc.
Cambrex Charles City, Inc
Catalent Pharma Solutions, LLC
Chattem Chemicals, Inc.
Curia New York, Inc.
Elite Laboratories, Inc.
Epic Pharma, LLC
Golden State Medical Supply, Inc.
Granules Pharmaceuticals Inc.
Lannett Company, Inc.
NorthStar RxLLC
Oryza Pharmaceuticals Inc.
Patheon Manufacturing Services LLC
Prasco Laboratories
Rhodes Pharmaceuticals L.P.
Sandoz Inc
Siegfried USA, LLC
SpecGx LLC
Sun Pharmaceutical Industries, Inc.
SUNRISE PHARMACEUTICAL, INC.
Takeda Pharmaceuticals America, Inc.
Teva Pharmaceuticals USA, Inc.
Teva Pharmaceuticals, Inc.
Veranova, L.P.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 12 drug and cosmetic product listings (FDA).

  • •Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate and Amphetamine Sulfate
  • •Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate and Amphetamine Sulfate
  • •Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CII
  • •Mydayis
  • •Dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, amphetamine sulfate
  • •Mixed Salts of a Single-Entity Amphetamine Product
  • •Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine Sulfate
  • •Mixed Salts of a Single Entity Amphetamine Product XR
Show all 12
  • •Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate, Amphetamine Sulfate Extended-Release
  • •Adderall
  • •Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate, and Amphetamine Sulfate Extended-Release
  • •Adderall XR
FDA Shortage Status
Active Shortage
Shortage History
  • Current shortage

    Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet

    Shortage listed since October 12, 2022

    Manufacturer reports: 1 unavailable, 3 limited, 2 available

See all current drug shortages

Chemical Identity

CAS851591-76-9
PubChem CID71587816
DTXSIDDTXSID50234313
FormulaC22H35N3O5
Mol. Weight421.5 g/mol
SMILESCC(CC1=CC=CC=C1)N.CC(CC1=CC=CC=C1)N.C(C(C(=O)O)N)C(=O)O.O

Data Sources

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Brief citations

Amphetamine aspartate monohydrate (CAS 851591-76-9) https://chemicalindependence.com/chemical/851591-76-9/ PubChem: 71587816. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/71587816 FDA National Drug Code directory: CAS 851591-76-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 851591-76-9. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 292249 for CAS 851591-76-9. Reporting year: 2024. https://usatrade.census.gov/