Cabozantinib

Drug ingredient

CAS 849217-68-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$111M

Top sourceIndia 28%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293349 · basket

These shares come from HS customs code 293349, which covers 94 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 28%IndiaCN 27%ChinaSE 12%SwedenKR 10%South KoreaGB 4%United Kingdom

Spain
Portugal
Germany
Netherlands
Israel
Australia
Taiwan
Lithuania
South Africa
Hong Kong

4 FDA-registered drug labelers

Dr Reddys Laboratories Limited

MSN Laboratories Private Limited

Sterling Chemical Malta Ltd

STERLING SPA

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$9.84/gAaron Chemicals LLC

CountryHong Kong

Pack$246.00 / 25 g

Purity98%

Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

19 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$9.96	25 g	98%
A2B Chem LLC	United States	$30.00	5 g	98%
Combi-Blocks, Inc.	United States	$30.40	25 g	98%
AA BLOCKS	United States	$33.20	5 g	98%
BLD Pharmatech Co., Limited	United States	$38.00	10 g	98%
Ambeed, Inc.	United States	$38.00	10 g	98%
AstaTech, Inc	United States	$41.70	10 g	98%
BLD Pharmatech GmbH	Germany	$42.00	5 g	98%
BLD Pharmatech Ltd.	China	$42.00	5 g	98%
AK Scientific, Inc.	United States	$56.20	5 g	98%
Angene International Limited	United States	$71.10	10 g	98%
TargetMol Chemicals	China → United States	$524.00	500 mg	99.88%
MedKoo Biosciences, Inc	United States	$850.00	5 g	98%
MedChemExpress MCE	Sweden	$951.06	500 mg	99.97%
Apexbio Technology LLC	United States	$1320.00	100 mg	98.6%
ChemFaces	China	$1500.00	20 mg	98%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	95%
Cayman Europe	Estonia	$16826.60	50 mg	98%

Chemical Identity

CAS849217-68-1

PubChem CID25102847

DTXSIDDTXSID10233968

FormulaC28H24FN3O5

Mol. Weight501.5 g/mol

SMILESCOC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F

Data Sources

PubChem · compound 25102847Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Cabozantinib (CAS 849217-68-1) https://chemicalindependence.com/chemical/849217-68-1/ PubChem: 25102847. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/25102847 FDA National Drug Code directory: CAS 849217-68-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293349 for CAS 849217-68-1. Reporting year: 2024. https://usatrade.census.gov/