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Itraconazole

Drug ingredient

CAS 84625-61-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 84625-61-6
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
34 FDA-registered drug labelers
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Alivus Life Sciences Limited
American Health Packaging
Amneal Pharmaceuticals LLC
Ascend Laboratories, LLC
AURORE PHARMACEUTICALS PRIVATE LIMITED
AvPAK
Camber Pharmaceuticals, Inc.
COHANCE LIFESCIENCES LIMITED
DARMERICA, LLC
Derivados Quimicos SAU
Janssen Pharmaceutica NV
Janssen Pharmaceutical Sciences Unlimited Company
Janssen Pharmaceuticals, Inc.
Kalchem International inc
LETCO MEDICAL, LLC
Matrix Pharmacorp Private Limited
Mayne Pharma Commercial LLC
Mayne Pharma International Pty Ltd
Medisca Inc.
Natco Pharma USA LLC
Neuland Laboratories Limited
NorthStar RxLLC
Patriot Pharmaceuticals
Professional Compounding Centers of America dba PCCA
Quimica Sintetica S.A.
Rising Pharma Holdings, Inc.
Smilax Laboratories Limited
SMS Pharmaceuticals Limited
Spectrum Laboratory Products, Inc.
Torrent Pharmaceuticals Limited
Vasudha Pharma Chem Limited
W. R. Grace & Co.-Conn.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

  • •Itraconazole
  • •Tolsura
  • •Sporanox
  • •Itraconazole Oral
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Itraconazole Capsule

    Shortage listed since February 27, 2026

See all current drug shortages

Vendor Pricing

$1.96/gCombi-Blocks, Inc.
CountryUnited States
Pack$980.00 / 500 g
Purity98%
Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

10 more vendors
VendorCountry$/gPackPurity
A2B Chem LLCUnited States$2.08500 g95%
AA BLOCKSUnited States$2.19500 g95%
BLD Pharmatech GmbHGermany$3.35100 g98%
BLD Pharmatech Ltd.China$3.35100 g98%
AstaTech, IncUnited States$3.99100 g95%
Ambeed, Inc.United States$8.405 g98%
Apexbio Technology LLCUnited States$275.001 g99.58%
Fulfilled by MolportLatvia$600.005 mg99.97%
Sigma-Aldrich (Rush Stock)Germany$1635.60200 mg—
Sigma-AldrichGermany$1635.60200 mg—

Chemical Identity

CAS84625-61-6
PubChem CID55283
DTXSIDDTXSID3023180
FormulaC35H38Cl2N8O4
Mol. Weight705.6 g/mol
SMILESCCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl

Data Sources

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Brief citations

Itraconazole (CAS 84625-61-6) https://chemicalindependence.com/chemical/84625-61-6/ PubChem: 55283. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/55283 FDA National Drug Code directory: CAS 84625-61-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 84625-61-6. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293499 for CAS 84625-61-6. Reporting year: 2024. https://usatrade.census.gov/