Lamotrigine

Drug ingredient

CAS 84057-84-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 84057-84-1
US productionNot reported
Import value, 2024$309M
Top sourceChina 40%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293369 · basket

These shares come from HS customs code 293369, which covers 192 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 40%ChinaJP 19%JapanIN 15%IndiaES 11%SpainDE 5%Germany
62 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Adare Pharmaceuticals Inc
Advagen Pharma Limited
Advanced Rx Pharmacy of Tennessee, LLC
Ajanta Pharma USA Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals of New York LLC
Ascend Laboratories, LLC
Asclemed USA, Inc.
Aurobindo Pharma Limited
AvKARE
AX Pharmaceutical Corp
Bryant Ranch Prepack
Camber Pharmaceuticals Inc
Cardinal Health 107, LLC
COHANCE LIFESCIENCES LIMITED
Coupler LLC
CTX Lifesciences Pvt. Ltd.
DIRECT RX
Divi's Laboratories Limited
Dr. Reddys Laboratories Inc.
Dr.Reddy's Laboratories Limited
Endo USA, Inc.
GlaxoSmithKline LLC
Glenmark Pharmaceuticals Inc., USA
IOL Chemicals and Pharmaceuticals Ltd.
Jubilant Biosys limited
Jubilant Cadista Pharmacuticals Inc.
Major Pharmaceuticals
Matrix Pharmacorp Private Limited
Medichem S.A.
NCS HealthCare of KY, LLC dba Vangard Labs
Nordic Pharma, Inc.
NorthStar Rx LLC
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
Optimus Drugs Private Limited
OWP Pharmaceuticals, Inc.
Par Health USA, LLC
PD-Rx Pharmaceuticals, Inc.
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America
Proficient Rx LP
Quallent Pharmaceuticals Health LLC
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
ScieGen Pharmaceuticals, Inc.
SMS Pharmaceuticals Limited
ST. MARY'S MEDICAL PARK PHARMACY
Sun Pharmaceutical Industries, Inc.
Torrent Pharmaceuticals Limited
Unichem Laboratories Limited, India
Unichem Pharmaceuticals (USA), Inc.
Yiling Pharmaceutical, Inc.
Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.
Zhejiang Supor Pharmaceuticals Co., Ltd
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •Lamotrigine
  • •Lamotrigine ER
  • •Lamotrigine Extended-Release
  • •Lamictal
  • •Subvenite
  • •Lamictal XR
  • •Lamictal ODT
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Lamotrigine Tablet, Extended Release

    Shortage listed since April 29, 2026

See all current drug shortages

Vendor Pricing

$1.17/gAaron Chemicals LLC
CountryHong Kong
Pack$585.00 / 500 g
Purity98%
Vendors29 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS84057-84-1
PubChem CID3878
DTXSIDDTXSID2023195
FormulaC9H7Cl2N5
Mol. Weight256.09 g/mol
SMILESC1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N

Data Sources

Brief citations

Lamotrigine (CAS 84057-84-1) https://chemicalindependence.com/chemical/84057-84-1/ PubChem: 3878. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3878 FDA National Drug Code directory: CAS 84057-84-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 84057-84-1. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293369 for CAS 84057-84-1. Reporting year: 2024. https://usatrade.census.gov/