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Phytonadione

Drug ingredient

CAS 84-80-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 84-80-0
US productionNot reported
Import value, 2024$295M
Top sourceChina 56%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293629 · basket

These shares come from HS customs code 293629, which covers 17 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 56%ChinaCH 12%SwitzerlandIN 12%IndiaIT 11%ItalyJP 2%Japan
42 FDA-registered drug labelers
Agnitio Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals NY LLC
Amphastar Nanjing Pharmaceuticals, Inc.
Apothecon Pharmaceuticals Pvt Ltd
AvKARE
Baxter Healthcare Corporation
Bottled Science, Inc.
Caplin Steriles Limited
Chongqing Biocare Pharmaceutical Ltd.
Cipla USA Inc.
Coupler LLC
Dr.Reddy's Laboratories Inc
DSM Nutritional Products Ltd.
DSM Nutritional Products, LLC
Emcure Pharmaceuticals Limited
Enaltec Labs Pvt Ltd
Exelan Pharmaceuticals, Inc.
Fresenius Kabi USA, LLC
Gland Pharma Limited
GLENMARK PHARMACEUTICALS INC
Henry Schein, Inc.
HF Acquisition Co LLC, DBA HealthFirst
Hospira, Inc.
International Medication Systems, Limited
Major Pharmaceuticals
MSN Laboratories Private Limited
Northstar Rx LLC.
Orbicular Pharmaceutical Technologies Private Limited
Professional Compounding Centers of America dba PCCA
PureTek Corporation
Sagent Pharmaceuticals
Sandoz Inc
ScieGen Pharmaceuticals Inc
Sionc Pharmaceutical Private Limited
Veranova, L.P.
Xiromed LLC
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

  • •Phytonadione Phytonadione
  • •Phytonadione
  • •Vitalipid N
  • •Vitamin K1 Phytonadione
  • •MD Post Care
  • •Vitamin K1
  • •Pediatric Infuvite Multiple Vitamins
  • •Diatrol
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$11.60/gCombi-Blocks, Inc.
CountryUnited States
Pack$290.00 / 25 g
Purity98%
Vendors6 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

5 more vendors
VendorCountry$/gPackPurity
AA BLOCKS (1 week)United States$15.205 g98%
Aaron Chemicals LLCHong Kong$16.805 g98%
MolnovaChina$33.001 g99%
MedKoo Biosciences, IncUnited States$42.5020 g98%
AA BLOCKSUnited States$4880.0025 mg99.79%

Chemical Identity

CAS84-80-0
PubChem CID5284607
DTXSIDDTXSID8023472
FormulaC31H46O2
Mol. Weight450.7 g/mol
SMILESCC1=C(C(=O)C2=CC=CC=C2C1=O)CC=C(C)CCCC(C)CCCC(C)CCCC(C)C

Data Sources

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Brief citations

Phytonadione (CAS 84-80-0) https://chemicalindependence.com/chemical/84-80-0/ PubChem: 5284607. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5284607 EPA TSCA Inventory: CAS 84-80-0. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293629 for CAS 84-80-0. Reporting year: 2024. https://usatrade.census.gov/