Methylprednisolone
Drug ingredientActive ShortageCAS 83-43-2
This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.
EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293729 · basket
These shares come from HS customs code 293729, which covers 57 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
- Netherlands
- Australia
- Malaysia
- Portugal
- United Kingdom
- Japan
- Malta
- Canada
- Israel
- Singapore
- New Zealand
- Poland
- Ukraine
- Belgium
- Sweden
34 FDA-registered drug labelers
Why It Matters
Appears in 2 drug and cosmetic product listings (FDA).
- •Methylprednisolone
- •Medrol
- Current shortage
Methylprednisolone Acetate Injection
Shortage listed since December 15, 2021
Manufacturer reports: 2 unavailable, 1 limited, 1 available
Vendor Pricing
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
17 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| AA BLOCKS | United States | $26.08 | 25 g | 98% |
| AstaTech, Inc | United States | $79.80 | 5 g | 98% |
| AK Scientific, Inc. | United States | $81.40 | 5 g | 98% |
| MedChemExpress MCE | Sweden | $112.53 | 5 g | 99.78% |
| Cayman Europe | Estonia | $128.52 | 5 g | 98% |
| Apexbio Technology LLC | United States | $200.00 | 1 g | 99.31% |
| Sigma-Aldrich (Rush Stock) | Germany | $369.00 | 500 mg | — |
| Sigma-Aldrich | Germany | $369.00 | 500 mg | — |
| Interbioscreen | Hong Kong | $401.00 | 10 g | 95% |
| Labotest KG | Germany | $453.00 | 1000 mg | 90% |
| MedKoo Biosciences, Inc | United States | $485.00 | 1 g | 98% |
| Axon Medchem | Netherlands | $840.00 | 250 mg | 99% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 90% |
| Princeton BioMolecular Research (SC) | United States | $2900.00 | 100 mg | 90% |
| Vitas M Chemical Limited | Hong Kong | $3170.00 | 100 mg | 90% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 97% |
| TimTec, LLC | United States | $9333.33 | 30 mg | 90% |
Chemical Identity
Data Sources
- PubChem · compound 6741Retrieved 2026-04-07
- EPA TSCA InventoryRetrieved 2026-04-24
- FDA Drug ShortagesRetrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Methylprednisolone (CAS 83-43-2) https://chemicalindependence.com/chemical/83-43-2/ PubChem: 6741. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6741 EPA TSCA Inventory: CAS 83-43-2. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 83-43-2. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293729 for CAS 83-43-2. Reporting year: 2024. https://usatrade.census.gov/