Quinapril hydrochloride

Drug ingredientActive Shortage

CAS 82586-55-8

This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.

Molecular structure of 82586-55-8
1 HCl
US productionNot reported
Import value, 2024$111M
Top sourceIndia 28%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293349 · basket

These shares come from HS customs code 293349, which covers 94 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IN 28%IndiaCN 27%ChinaSE 12%SwedenKR 10%South KoreaGB 4%United Kingdom
12 FDA-registered drug labelers
Aarti Pharmalabs Limited
Aurobindo Pharma Limited
BluePoint Laboratories
Bryant Ranch Prepack
Chartwell RX, LLC
Cipla USA Inc.
Farmhispania, S.A.
Lupin Pharmaceuticals, Inc.
Northwind Health Company, LLC
Proficient Rx LP
Rolabo Outsourcing S.L.
Solco Healthcare US, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •Quinapril
  • •Quinapril and Hydrochlorothiazide
  • •Quinapril HCL and Hydrochlorothiazide
  • •Quinapril Hydrochloride/Hydrochlorothiazide
  • •Quinapril and Hydrochlorothiazide 20/25
  • •Quinapril and Hydrochlorothiazide 10/12.5
  • •Quinapril and Hydrochlorothiazide 20/12.5
FDA Shortage Status
Active Shortage
Shortage History
  • Current shortage

    Quinapril Hydrochloride Tablet

    Shortage listed since January 19, 2023

    Manufacturer reports: 1 unavailable, 1 available

  • to be discontinued

    Hydrochlorothiazide; Quinapril Hydrochloride Tablet

    Shortage listed since October 1, 2025

See all current drug shortages

Vendor Pricing

$5.39/gAaron Chemicals LLC
CountryHong Kong
Pack$539.00 / 100 g
Purity99%
Vendors23 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS82586-55-8
PubChem CID54891
DTXSIDDTXSID3021221
FormulaC25H31ClN2O5
Mol. Weight475 g/mol
SMILESCCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O.Cl

Data Sources

Brief citations

Quinapril hydrochloride (CAS 82586-55-8) https://chemicalindependence.com/chemical/82586-55-8/ PubChem: 54891. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/54891 FDA National Drug Code directory: CAS 82586-55-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 82586-55-8. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293349 for CAS 82586-55-8. Reporting year: 2024. https://usatrade.census.gov/