Lumefantrine

Drug ingredient

CAS 82186-77-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$197M

Top sourceChina 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292219 · basket

These shares come from HS customs code 292219, which covers 167 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 36%ChinaIT 15%ItalyDE 14%GermanyIN 7%IndiaHU 5%Hungary

Saudi Arabia
Lithuania
Canada
Ukraine
Israel
Singapore
Mexico
Ireland
Netherlands
Malaysia
Slovakia
Denmark
Finland
Latvia
Greece
Austria

3 FDA-registered drug labelers

Calyx Chemicals & Pharmaceuticals Limited

Novartis Pharmaceuticals Corporation

Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Coartem

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.90/gAaron Chemicals LLC

CountryHong Kong

Pack$448.00 / 500 g

Purity98%

Vendors5 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

4 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$1.07	500 g	98%
MedKoo Biosciences, Inc	United States	$38.00	25 g	98%
Fulfilled by Molport	Latvia	$50.00	100 mg	98%
Molnova	China	$356.00	500 mg	99%

Chemical Identity

CAS82186-77-4

PubChem CID6437380

DTXSIDDTXSID3046663

FormulaC30H32Cl3NO

Mol. Weight528.9 g/mol

SMILESCCCCN(CCCC)CC(C1=CC(=CC2=C1C3=C(C2=CC4=CC=C(C=C4)Cl)C=C(C=C3)Cl)Cl)O

Data Sources

PubChem · compound 6437380Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Lumefantrine (CAS 82186-77-4) https://chemicalindependence.com/chemical/82186-77-4/ PubChem: 6437380. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6437380 FDA National Drug Code directory: CAS 82186-77-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292219 for CAS 82186-77-4. Reporting year: 2024. https://usatrade.census.gov/