2-Amino-1-naphthalenesulfonic acid

CAS 81-16-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$2M

Top sourceCanada 48%

At least one company claimed its 2019 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292145 · basket

EPA reports by year

2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292145, which covers 23 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 48%CanadaIN 35%IndiaCN 10%ChinaCH 7%SwitzerlandJP 1%Japan

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Sumitomo · JP Japan

Sumitomo Corp Of Americas

Why It Matters

Sectors

Textiles

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 1 sector as 2 functional roles.

•Intermediate in Synthetic Dye and Pigment Manufacturing (0%)Processing as a reactant
•Pigment in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.02/gAaron Chemicals LLC

CountryHong Kong

Pack$8.00 / 500 g

Purity98%

Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

19 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.02	500 g	98%
A2B Chem LLC	United States	$0.03	500 g	98%
AA BLOCKS	United States	$0.03	500 g	98%
BLD Pharmatech Ltd.	China	$0.04	1 kg	98%
BLD Pharmatech GmbH	Germany	$0.06	500 g	98%
Fluorochem EU	Germany	$0.07	500 g	98%
ALFA AESAR	Germany	$0.10	2.5 kg	98%
BLD Pharmatech Co., Limited	United States	$0.11	1 kg	98%
Ambeed, Inc.	United States	$0.11	1 kg	98%
AK Scientific Specialized	United States	$0.19	500 g	95%
Combi-Blocks, Inc.	United States	$0.25	1 kg	98%
Angene International Limited	United States	$0.36	500 g	95%
AK Scientific, Inc.	United States	$0.67	100 g	98%
AstaTech (2 weeks)	United States	$3.68	25 g	95%
Labotest KG	Germany	$217.80	5000 mg	90%
Vitas M Chemical Limited	Hong Kong	$272.00	1 g	90%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
ChemBridge Corporation	Kazakhstan	$18000.00	5 mg	90%

Chemical Identity

CAS81-16-3

PubChem CID6670

DTXSIDDTXSID7020922

FormulaC10H9NO3S

Mol. Weight223.25 g/mol

SMILESC1=CC=C2C(=C1)C=CC(=C2S(=O)(=O)O)N

Data Sources

EPA CompTox (DSSTox) · DTXSID7020922Retrieved 2026-04-06
PubChem · compound 6670Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2-Amino-1-naphthalenesulfonic acid (CAS 81-16-3) https://chemicalindependence.com/chemical/81-16-3/ EPA CompTox (DSSTox): DTXSID7020922. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7020922 PubChem: 6670. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6670 EPA Chemical Data Reporting: 81-16-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 81-16-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292145 for CAS 81-16-3. Reporting year: 2024. https://usatrade.census.gov/