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Saccharin

Drug ingredient

CAS 81-07-2

Companies reported imports and no US production of this drug ingredient to EPA for 2023.

Molecular structure of 81-07-2
US productionZero
Import value, 2024$18M
Import volume2.7M lb
Import dependency100%
Top sourceSouth Korea 56%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Saccharin · US import value by year
$24M2013$27M2016$18M2024$16M2025

2013: $24M · Peak 2016: $27M · 2024: $18M · 2025: $16M

Where It Comes From

Customs basis: HS 292511 · narrow

EPA reports by year
2023
US production Zero · Imports 2.7M lb
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 292511, which covers 5 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
KR 56%South KoreaCN 23%ChinaIN 20%IndiaID 1%Indonesia
EPA-registered importers (1)
Target
4 FDA-registered drug labelers
Apex Energetics Inc.
Newton Laboratories, Inc.
Nutritional Specialties, Inc.
Professional Complementary Health Formulas

Why It Matters

Sectors
HealthElectronicsConstruction
Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

  • •Defense
  • •Allergies
  • •Artificial Sweetener Detox 6034
  • •Immune System Stimulator Drops 2033
  • •Food Additives
  • •B05 Gluco Balance
FDA Shortage Status
No FDA shortage records

Industrial Uses

  • •Adhesives and sealant chemicals in Adhesive Manufacturing (90%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.02/gAaron Chemicals LLC
CountryHong Kong
Pack$11.00 / 500 g
Purity98%
Vendors35 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

34 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.03500 g98%
AA BLOCKSUnited States$0.041 kg98%
A2B Chem LLCUnited States$0.041 kg98%
BLD Pharmatech GmbHGermany$0.051 kg98%
BLD Pharmatech Ltd.China$0.051 kg98%
ChemsceneUnited States$0.051 kg—
Fluorochem EUGermany$0.061 kg95%
BLD Pharmatech Co., LimitedUnited States$0.111 kg98%
Ambeed, Inc.United States$0.111 kg98%
Fluorochem UKUnited Kingdom$0.11100 g95%
ALFA AESARGermany$0.172.5 kg98%
Sigma-Aldrich (Rush Stock)Germany$0.18500 g98%
Sigma-AldrichGermany$0.18500 g98%
AK Scientific SpecializedUnited States$0.24500 g95%
Combi-Blocks, Inc.United States$0.251 kg97%
AK Scientific, Inc.United States$0.28500 g98%
AstaTech, IncUnited States$0.33100 g95%
Angene International LimitedUnited States$0.44500 g95%
SynthonixUnited States$0.7625 g95%
MedChemExpress MCESweden$3.6150 g99.94%
InterbioscreenHong Kong$5.0010 g95%
AldlabUnited States$5.521 g95%
TargetMol ChemicalsChina → United States$31.001 g98.51%
MolnovaChina$74.00500 mg99%
Vitas M Chemical LimitedHong Kong$360.001 g90%
Labotest KGGermany$453.001000 mg90%
Otava, Ltd.Ukraine$2280.0050 mg95%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg95%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
Life Chemicals Inc.Ukraine → Canada$3100.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
AsinexNetherlands$6461.40100 mg90%
Key Organics Ltd.United Kingdom$6900.0010 mg95%
TimTec, LLCUnited States$90000.002 mg90%

Chemical Identity

CAS81-07-2
PubChem CID5143
DTXSIDDTXSID5021251
FormulaC7H5NO3S
Mol. Weight183.19 g/mol
SMILESC1=CC=C2C(=C1)C(=O)NS2(=O)=O

Data Sources

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Brief citations

Saccharin (CAS 81-07-2) https://chemicalindependence.com/chemical/81-07-2/ EPA CompTox (DSSTox): DTXSID5021251. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5021251 PubChem: 5143. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/5143 EPA Chemical Data Reporting: 81-07-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 81-07-2. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292511 for CAS 81-07-2. Reporting year: 2024. https://usatrade.census.gov/