Nigrosine

CAS 8005-03-6

U.S. production volumes are classified as confidential business information.

Molecular structure of 8005-03-6 — 2 Na⁺

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$56M

Top sourceIndia 70%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 320412 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 320412, which covers 106 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 70%IndiaMY 7%MalaysiaCH 4%SwitzerlandCN 4%ChinaDE 3%Germany

Ireland
United Kingdom
Spain
South Korea
Denmark
Pakistan
Hong Kong
Czech Republic
Brazil
Turkey

Domestic parents -- activity not disclosed (3)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Johns Manville

Lanxess

Milliken &

EPA-registered importers (3)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Syensqo Sa · BE Belgium

Munzing

Solvay

Why It Matters

Sectors

Plastics & RubberPaper & Printing

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 3 functional roles.

•Pigment in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Dye in Printing and Related Support Activities (100%)Processing—incorporation into formulation, mixture, or reaction product
•Dyes in Not Known or Reasonably Ascertainable (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$29.00/gTargetMol Chemicals

CountryChina (registered: United States)

Pack$29.00 / 1 g

Purity99.99%

Vendors1 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS8005-03-6

PubChem CID135442942

DTXSIDDTXSID1020934

FormulaC22H14N6Na2O9S2

Mol. Weight616.5 g/mol

SMILESC1=CC=C(C=C1)N=NC2=C(C3=C(C(=C(C=C3C=C2S(=O)(=O)[O-])S(=O)(=O)[O-])N=NC4=CC=C(C=C4)[N+](=O)[O-])N)O.[Na+].[Na+]

Data Sources

EPA CompTox (DSSTox) · DTXSID1020934Retrieved 2026-04-06
PubChem · compound 135442942Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Nigrosine (CAS 8005-03-6) https://chemicalindependence.com/chemical/8005-03-6/ EPA CompTox (DSSTox): DTXSID1020934. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020934 PubChem: 135442942. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/135442942 EPA Chemical Data Reporting: 8005-03-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 8005-03-6. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 320412 for CAS 8005-03-6. Reporting year: 2024. https://usatrade.census.gov/