Flag of the United StatesAmerican Chemical Independence

Threonine

Drug ingredient

CAS 80-68-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 80-68-2
US productionNot reported
Import value, 2024$652M
Top sourceSingapore 77%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292250 · basket

These shares come from HS customs code 292250, which covers 76 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 77%SingaporeCN 12%ChinaIT 4%ItalyIN 2%IndiaGB 1%United Kingdom
14 FDA-registered drug labelers
Ajinmoto Health & Nutrition North America Inc.
Ajinomoto Health & Nutrition North America Inc.
B. Braun Medical Inc.
Baxter Healthcare Company
Baxter Healthcare Corporation
Fresenius Kabi USA, LLC
Guna spa
ICU Medical Inc.
KYOWA HAKKO BIO CO., LTD.
Nutritional Specialties, Inc.
Professional Complementary Health Formulas
Shanghai Ajinomoto Amino Acid Co.,Ltd.
Shanghai Plumino Amino Acid Co., Ltd.
Temple Health Nutrition, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 16 drug and cosmetic product listings (FDA).

  • •Aminosyn-PF
  • •Plenamine
  • •Kabiven
  • •Clinimix
  • •Clinimix E
  • •Clinisol
  • •ProSol
  • •TrophAmine
Show all 16
  • •TH-101
  • •Aminosyn II
  • •Osteobios
  • •Travasol
  • •Perikabiven
  • •L-Threonine High 7426
  • •Metab
  • •Premasol - sulfite-free (Amino Acid)
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.49/gAaron Chemicals LLC
CountryHong Kong
Pack$245.00 / 500 g
Purity95%
Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.56500 g95%
Combi-Blocks, Inc.United States$0.78500 g95%
BLD Pharmatech Ltd.China$0.81500 g95%
BLD Pharmatech Co., LimitedUnited States$0.89500 g95%
Ambeed, Inc.United States$0.89500 g95%
A2B Chem LLCUnited States$0.90500 g98%
AA BLOCKSUnited States$0.95500 g95%
SynthonixUnited States$1.00100 g95%
BLD Pharmatech GmbHGermany$1.2425 g95%
AK Scientific, Inc.United States$3.1625 g95%
InterbioscreenHong Kong$24.0010 g95%
Labotest KGGermany$217.805000 mg90%
MolnovaChina$380.00100 mg99%
TargetMol ChemicalsChina → United States$500.00100 mg99.88%
Otava, Ltd.Ukraine$2280.0050 mg95%
AngeneChina → Hong Kong$4266.6730 mg95%
Vitas M Chemical LimitedHong Kong$46000.001 mg90%

Chemical Identity

CAS80-68-2
PubChem CIDNot recorded
DTXSIDDTXSID70893087
FormulaC4H9NO3
Mol. Weight119.12 g/mol
SMILESC[C@@H](O)[C@H](N)C(O)=O

Data Sources

← Back to Dashboard← Back to Health

Brief citations

Threonine (CAS 80-68-2) https://chemicalindependence.com/chemical/80-68-2/ EPA TSCA Inventory: CAS 80-68-2. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: CAS 80-68-2. Retrieved 2026-10-04. https://open.fda.gov/data/ndc/ US Census international trade: HS 292250 for CAS 80-68-2. Reporting year: 2024. https://usatrade.census.gov/