Homatropine methylbromide

Drug ingredient

CAS 80-49-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$171M

Top sourceSwitzerland 40%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293979 · basket

These shares come from HS customs code 293979, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 40%SwitzerlandCN 18%ChinaIT 14%ItalyDE 13%GermanyIN 10%India

Australia
Poland
Belgium
Taiwan
Canada
Japan
Spain
Mexico
New Zealand
Slovenia
Israel

13 FDA-registered drug labelers

Actavis Pharma, Inc.

C-SQUARED PHARMA LIMITED

C-Squared Pharma Sarl

Genus Lifesciences Inc.

Hubei Biocause Heilen Pharmaceutical Co., Ltd

KVK-Tech, Inc.

Laurus Labs Limited

Lupin Pharmaceuticals,Inc.

Novel Laboratories, Inc.

PAI Holdings, LLC dba PAI Pharma

Professional Compounding Centers of America

Professional Compounding Centers of America dba PCCA

SCL Lifesciences Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

•Hydrocodone Bitartrate and Homatropine Methylbromide
•Hydromet
•Hycodan

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Homatropine Methylbromide and Hydrocodone Bitartrate Syrup
Shortage listed since September 11, 2025

See all current drug shortages

Vendor Pricing

$24.32/gAstaTech (2 weeks)

CountryUnited States

Pack$608.00 / 25 g

Purity95%

Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

3 more vendors

Vendor	Country	$/g	Pack	Purity
MedKoo Biosciences, Inc	United States	$34.00	25 g	98%
Molnova	China	$244.00	500 mg	99%
Labotest KG	Germany	$453.00	1000 mg	90%

Chemical Identity

CAS80-49-9

PubChem CID6646

DTXSIDDTXSID4023127

FormulaC17H24BrNO3

Mol. Weight370.3 g/mol

SMILESC[N+]1(C2CCC1CC(C2)OC(=O)C(C3=CC=CC=C3)O)C.[Br-]

Data Sources

PubChem · compound 6646Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Homatropine methylbromide (CAS 80-49-9) https://chemicalindependence.com/chemical/80-49-9/ PubChem: 6646. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6646 EPA TSCA Inventory: CAS 80-49-9. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 80-49-9. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293979 for CAS 80-49-9. Reporting year: 2024. https://usatrade.census.gov/