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Dapsone

Drug ingredient

CAS 80-08-0

EPA’s 2023 records show zero U.S. production for this drug ingredient.

Molecular structure of 80-08-0
US productionZero
Import value, 2024$760M
Import volumeCBI
Top sourceChina 33%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293090 · basket

EPA reports by year
2023
US production Zero · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293090, which covers 418 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 33%ChinaES 14%SpainCH 9%SwitzerlandIT 7%ItalyIN 7%India
EPA-registered importers (4)
Toray Industries · JP Japan
Atul Usa
Huntsman
Toray Composite Materials America
45 FDA-registered drug labelers
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Allergan, Inc.
Almirall, LLC
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals NY LLC
ANI Pharmaceuticals, Inc.
Atul Ltd
Aurobindo Pharma Limited
AvKARE
AX Pharmaceutical Corp
Boswell Pharmacy Services LLC d/b/a BPS Wholesale
Chartwell RX, LLC
Cohance Lifesciences Limited
Cosette Pharmaceuticals, Inc.
Coupler LLC
DARMERICA, LLC
Dipharma Francis Srl
Encube Ethicals, Inc.
Everest Life Sciences. LLC
Fagron Inc
Golden State Medical Supply, Inc.
Haleos Labs Limited
LETCO MEDICAL, LLC
Lundbeck Pharmaceuticals Italy S.p.A.
Mayne Pharma
Mayne Pharma Commercial LLC
Medilux Laboratories Private Limited
Mylan Pharmaceuticals Inc.
NORTHSTAR RX LLC
NURAY CHEMICALS PRIVATE LIMITED
Pacific Pharma, Inc.
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Rising Pharma Holdings, Inc.
Sai Life Sciences Limited
Seton Pharmaceuticals
Spectrum Laboratory Products, Inc.
STHREE CHEMICALS PRIVATE LIMITED
Sun Pharmaceutical Industries, Inc.
Torrent Pharmaceuticals Limited
Trupharma, LLC
Viona Pharmaceuticals Inc
Westminster Pharmaceuticals, LLC
Zydus Lifesciences Limited

Why It Matters

Sectors
HealthConstructionPlastics & Rubber
Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

  • •Dapsone
  • •Aczone
  • •Dapsone 100 mg
  • •Dapsone 25 mg
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Dapsone Gel

    Shortage listed since March 27, 2026

See all current drug shortages

Industrial Uses

Used in 2 sectors as 3 functional roles.

  • •Adhesion/cohesion promoter in Plastics Material and Resin Manufacturing (100%)Processing as a reactant
  • •Intermediate in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Hardener in Plastics Product Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.04/gAaron Chemicals LLC
CountryHong Kong
Pack$18.00 / 500 g
Purity98%
Vendors32 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

31 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.04500 g98%
AA BLOCKSUnited States$0.051 kg98%
BLD Pharmatech GmbHGermany$0.051 kg98%
BLD Pharmatech Ltd.China$0.051 kg98%
Fluorochem EUGermany$0.061 kg97%
A2B Chem LLCUnited States$0.081 kg98%
BLD Pharmatech Co., LimitedUnited States$0.111 kg98%
Ambeed, Inc.United States$0.111 kg98%
AK Scientific SpecializedUnited States$0.111 kg98%
Fluorochem UKUnited Kingdom$0.11100 g97%
Angene International LimitedUnited States$0.15500 g98%
AK Scientific, Inc.United States$0.151 kg99%
Fulfilled by MolportLatvia$0.2025 g98%
Combi-Blocks, Inc.United States$0.251 kg98%
ALFA AESARGermany$0.32500 g98%
Sigma-Aldrich (Rush Stock)Germany$0.77500 g97%
Sigma-AldrichGermany$0.77500 g97%
Cayman EuropeEstonia$0.80100 g98%
MedChemExpress MCESweden$2.19100 g99.76%
MedKoo Biosciences, IncUnited States$10.0025 g98%
TargetMol ChemicalsChina → United States$17.002 g99.84%
Apexbio Technology LLCUnited States$19.605 g99.64%
AstaTech (2 weeks)United States$43.0025 g95%
MolnovaChina$48.001 g99%
CliniSciences GmbHSwitzerland$82.56500 mg99%
Vitas M Chemical LimitedHong Kong$310.001 g90%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
ChemDiv, Inc.United States$4070.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
ChemBridge CorporationKazakhstan$18000.005 mg90%
TimTec, LLC (back-ordered)United States$32000.0015 mg94%

Chemical Identity

CAS80-08-0
PubChem CID2955
DTXSIDDTXSID4020371
FormulaC12H12N2O2S
Mol. Weight248.3 g/mol
SMILESC1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N

Data Sources

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Brief citations

Dapsone (CAS 80-08-0) https://chemicalindependence.com/chemical/80-08-0/ EPA CompTox (DSSTox): DTXSID4020371. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4020371 PubChem: 2955. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/2955 EPA Chemical Data Reporting: 80-08-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA Drug Shortages: CAS 80-08-0. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293090 for CAS 80-08-0. Reporting year: 2024. https://usatrade.census.gov/