Azelastine hydrochloride

Drug ingredient

CAS 79307-93-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 79307-93-0
1 HCl
US productionNot reported
Import value, 2024$1.4B
Top sourceIreland 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
41 FDA-registered drug labelers
A-S Medication Solutions
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Allegiant Health
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals NY LLC
Apotex Corp.
Ascend Laboratories, LLC
Aurobindo Pharma Limited
Aurohealth LLC
AvKARE
AX Pharmaceutical Corp
Bayer HealthCare LLC.
Bryant Ranch Prepack
Coral Drugs Private Limited
Curia Italy S.r.l.
CVS PHARMACY, INC
Daito Pharmaceutical Co., Ltd
DARMERICA, LLC
Esteve Quimica, SA
Evonik Operations GmbH
Fosun Pharma USA Inc
Gland Pharma Limited
LETCO MEDICAL, LLC
MSN Laboratories Private Limited
Mylan Pharmaceuticals Inc.
NorthStar Rx LLC
Padagis Israel Pharmaceuticals Ltd
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Sandoz Inc
Somerset Therapeutics, LLC
Sun Pharmaceutical Industries, Inc.
Teva Pharmaceuticals, Inc.
Urquima, S.A.
Viatris Specialty LLC
Walgreens
Zhejiang Lepu Pharmaceutical Co., Ltd.
Zydus Lifesciences Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

  • •Azelastine Hydrochloride AND Fluticasone Propionate
  • •Azelastine Hydrochloride
  • •Azelastine Hydrochloride Ophthalmic Solution 0.05%
  • •Azelastine
  • •Azelastine HCl
  • •Astepro Allergy
  • •Dymista
  • •Children Astepro Allergy
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Azelastine Hydrochloride; Fluticasone Propionate Nasal Spray

    Shortage listed since September 4, 2025

See all current drug shortages

Vendor Pricing

$10.70/gCombi-Blocks, Inc.
CountryUnited States
Pack$1070.00 / 100 g
Purity96%
Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS79307-93-0
PubChem CID54360
DTXSIDDTXSID2045945
FormulaC22H25Cl2N3O
Mol. Weight418.4 g/mol
SMILESCN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl

Data Sources

Brief citations

Azelastine hydrochloride (CAS 79307-93-0) https://chemicalindependence.com/chemical/79307-93-0/ PubChem: 54360. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/54360 FDA National Drug Code directory: CAS 79307-93-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 79307-93-0. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293399 for CAS 79307-93-0. Reporting year: 2024. https://usatrade.census.gov/