1-Chloropropan-2-one

CAS 78-95-5

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$175M

Top sourceIndia 48%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291479 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291479, which covers 95 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 48%IndiaCN 20%ChinaMX 19%MexicoDE 10%GermanyFI 2%Finland

Ukraine
Japan
Australia
Netherlands
South Korea
Canada
Switzerland
Russia
Poland
Italy
United Kingdom
Spain
Taiwan
Grenada

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Wacker Chemical Corporation - Headquarters

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

China National Chemical · CN China

Syngenta Crop Protection

Why It Matters

Sectors

Agriculture

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 1 functional role.

•Intermediate in Agriculture, Forestry, Fishing and HuntingProcessing as a reactant
•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.03/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$7023.76 / 220 kg

Purity96%

Vendors8 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

7 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$0.03	220 kg	96%
Interbioscreen	Hong Kong	$24.00	10 g	95%
Labotest KG	Germany	$217.80	5000 mg	90%
Otava, Ltd.	Ukraine	$2280.00	50 mg	95%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	95%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS78-95-5

PubChem CID6571

DTXSIDDTXSID0021547

FormulaC3H5ClO

Mol. Weight92.52 g/mol

SMILESCC(=O)CCl

Data Sources

EPA CompTox (DSSTox) · DTXSID0021547Retrieved 2026-04-06
PubChem · compound 6571Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1-Chloropropan-2-one (CAS 78-95-5) https://chemicalindependence.com/chemical/78-95-5/ EPA CompTox (DSSTox): DTXSID0021547. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0021547 PubChem: 6571. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6571 EPA Chemical Data Reporting: 78-95-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 78-95-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291479 for CAS 78-95-5. Reporting year: 2024. https://usatrade.census.gov/