Methyl ethyl ketone
Drug ingredientCAS 78-93-3
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$97M
Top sourceUnited Kingdom 36%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 291412 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
GB 36%United KingdomZA 29%South AfricaNL 15%NetherlandsDE 8%GermanyJP 6%Japan
- Canada
- Costa Rica
- India
EPA-registered manufacturers (5)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
United Initiators Gmbh · DE Germany
Carestream Health
Hudson Products
Solvchem
United Initiators
Domestic parents -- activity not disclosed (11)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Allchem Industries Holding
Cellmark Basic Materials
Chemical Distribution Network
Chemical Solvents
Colonial Group
Show all 11
Doremus Terminal
Dow Chemical
Eastman Chemical
Lanco Manufacturing
Soyventis North America
Tenneco Brake
EPA-registered importers (33)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Brenntag · DE Germany
Kh Chemicals International B V · NL Netherlands
Mercedes-Benz Ag · DE Germany
Sika Ag · CH Switzerland
Show all 33
Sumitomo Bakelite · JP Japan
American Gci Resitop
Arxada
Basf
Brenntag Global Marketing
Cascade Columbia
Daxx
Dover
Dupont Specialty Products Usa
Exxonmobil Product Solutions, A Div Of Exxon Mobil
Fortaleza Usa
Greenchem Industries
Henkel
Industrial Chemicals
Kh Chemicals Na
Lx Hausys America
Mercedes Benz U.S
Olin
Sasol Chemicals (Usa)
Shell Petroleum
Sika
Stahl Usa
Sumitomo Bakelite North America Holding
Superior Industrial Solutions
Systech Environmental
Tarr
The Sherwin Williams
Transchem
2 FDA-registered drug labelers
Nutritional Specialties, Inc.
Professional Complementary Health Formulas
Why It Matters
Sectors
Plastics & RubberPaints & CoatingsElectronicsTransportationPaper & PrintingCore ChemicalsHealthEnergyConsumer ProductsMetals & MiningTextilesConstruction
Downstream Uses
Appears in 2 drug and cosmetic product listings (FDA).
- •Industriox
- •Industriox 6011
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 25 sectors as 15 functional roles.
- •Diluent in All Other Basic Organic Chemical Manufacturing (8%)Processing—incorporation into formulation, mixture, or reaction product
- •Heat transferring agent in Wholesale and Retail Trade (75%)Processing—repackaging
- •Surface modifier in Paint and Coating Manufacturing (17%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Paint and Coating Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Printing Ink Manufacturing (70%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Oil and Gas Drilling, Extraction, and Support activities (100%)Use—non-incorporative activities
- •Solvent in Printing and Related Support ActivitiesUse—non-incorporative activities
- •Hardener in Transportation Equipment Manufacturing (100%)Processing—incorporation into article
- •Solvent in Transportation Equipment Manufacturing (10%)Processing—incorporation into article
- •Solvent in Fabricated Metal Product Manufacturing (10%)Processing—incorporation into article
- •Solvent in Electrical Equipment, Appliance, and Component Manufacturing (20%)Processing—incorporation into article
- •Solvent in Machinery Manufacturing (30%)Processing—incorporation into article
- •Solvent in Computer and Electronic Product Manufacturing (30%)Processing—incorporation into article
- •Solvent in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Plastics Material and Resin Manufacturing (10%)Use—non-incorporative activities
- •Intermediate in Miscellaneous Manufacturing (2%)Processing as a reactant
- •Intermediate in Synthetic Rubber Manufacturing (1%)Processing as a reactant
- •Solvent in Miscellaneous Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Adhesive Manufacturing (1%)Processing as a reactant
- •Binder in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •CBI in CBICBI
- •Solvent in Wood Product ManufacturingUse—non-incorporative activities
- •Solvent in Construction (1%)Use—non-incorporative activities
- •Solvent in Furniture and Related Product ManufacturingUse—non-incorporative activities
- •Fuel in Services (100%)Use—non-incorporative activities
- •Solvent in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Etching agent in Computer and Electronic Product Manufacturing (100%)Use—non-incorporative activities
- •Fuel in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing)Processing—repackaging
- •Polymerization promoter in Plastics Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into article
- •Adhesion/cohesion promoter in Transportation Equipment Manufacturing (100%)Processing—incorporation into article
- •Adhesion/cohesion promoter in Construction (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Surface modifier in Fabricated Metal Product ManufacturingUse—non-incorporative activities
- •Waterproofing agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (15%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Wholesale and Retail Trade (0%)Processing—repackaging
- •Dispersing agent in Paint and Coating ManufacturingNot Known or Reasonably Ascertainable
Chemical Identity
CAS78-93-3
PubChem CID6569
DTXSIDDTXSID3021516
FormulaC4H8O
Mol. Weight72.11 g/mol
SMILESCCC(=O)C
Data Sources
- EPA CompTox (DSSTox) · DTXSID3021516Retrieved 2026-04-06
- PubChem · compound 6569Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Methyl ethyl ketone (CAS 78-93-3) https://chemicalindependence.com/chemical/78-93-3/ EPA CompTox (DSSTox): DTXSID3021516. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021516 PubChem: 6569. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6569 EPA Chemical Data Reporting: 78-93-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 78-93-3. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291412 for CAS 78-93-3. Reporting year: 2024. https://usatrade.census.gov/