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Isophorone

CAS 78-59-1

Used in 6 industrial sectors tracked by the EPA.

Molecular structure of 78-59-1
US production30.3M lb
Import value, 2024$150M
Import volumeCBI
Top sourceIndia 25%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291429 · basket

EPA reports by year
2023
US production 30.3M lb · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 291429, which covers 163 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IN 25%IndiaES 18%SpainCN 12%ChinaIL 11%IsraelCH 9%Switzerland
EPA-registered manufacturers (1)
Evonik
Domestic parents -- activity not disclosed (3)
A.G. Layne
Brenntag Global Marketing
Cellmark Basic Materials
EPA-registered importers (3)
Brenntag · DE Germany
Emco Chemical Distributors
Transchem

Why It Matters

Sectors
AgricultureConstructionPlastics & RubberPaints & CoatingsPaper & PrintingCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 6 sectors as 4 functional roles.

  • •Solvent in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (37%)Processing as a reactant
  • •Solvent in Paint and Coating Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvent in Printing Ink Manufacturing (10%)Processing as a reactant
  • •Intermediate in Paint and Coating Manufacturing (48%)Processing as a reactant
  • •Solvent in Adhesive Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
  • •Adhesion/cohesion promoter in Plastics Material and Resin Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in All Other Chemical Product and Preparation Manufacturing (5%)Processing—incorporation into formulation, mixture, or reaction product
  • •Stabilizing agent in Plastics Material and Resin Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$6.00 / 500 g
Purity98%
Vendors24 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

23 more vendors
VendorCountry$/gPackPurity
AA BLOCKSUnited States$0.011 kg99%
A2B Chem LLCUnited States$0.02500 g99%
Angene ChemicalChina → Hong Kong$0.02500 g98%
Sigma-Aldrich (Rush Stock)Germany$0.0220 kg97%
Sigma-AldrichGermany$0.0220 kg97%
BLD Pharmatech GmbHGermany$0.031 kg99%
BLD Pharmatech Ltd.China$0.031 kg99%
BLD Pharmatech Co., LimitedUnited States$0.041 kg99%
Ambeed, Inc.United States$0.041 kg99%
ChemsceneUnited States$0.051 kg—
Fluorochem EUGermany$0.07500 g98%
SynthonixUnited States$0.08500 g95%
AK Scientific SpecializedUnited States$0.29100 g98%
AK Scientific, Inc.United States$0.41100 g99%
Angene International LimitedUnited States$0.80100 g98%
MedChemExpress MCESweden$0.81100 g99.95%
AstaTech, IncUnited States$0.99100 g97%
InterbioscreenHong Kong$24.0010 g95%
Labotest KGGermany$453.001000 mg90%
MolnovaChina$2260.0050 mg99%
Otava, Ltd.Ukraine$2280.0050 mg95%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg95%
AngeneChina → Hong Kong$4266.6730 mg98%

Chemical Identity

CAS78-59-1
PubChem CID6544
DTXSIDDTXSID8020759
FormulaC9H14O
Mol. Weight138.21 g/mol
SMILESCC1=CC(=O)CC(C1)(C)C

Data Sources

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Brief citations

Isophorone (CAS 78-59-1) https://chemicalindependence.com/chemical/78-59-1/ EPA CompTox (DSSTox): DTXSID8020759. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8020759 PubChem: 6544. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6544 EPA Chemical Data Reporting: 78-59-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 78-59-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291429 for CAS 78-59-1. Reporting year: 2024. https://usatrade.census.gov/