1-Ethynylcyclohexanol

CAS 78-27-3

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$118M

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceGermany 19%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290619 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290619, which covers 137 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 19%GermanyCH 17%SwitzerlandBR 17%BrazilIN 11%IndiaIT 10%Italy

Netherlands
Ukraine
Canada
United Kingdom
Malaysia
Australia
Indonesia
Czech Republic
Belgium

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Basf

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant

Vendor Pricing

$0.08/gAaron Chemicals LLC

CountryHong Kong

Pack$39.00 / 500 g

Purity97%

Vendors15 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

14 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.08	500 g	97%
AA BLOCKS	United States	$0.14	500 g	98%
A2B Chem LLC	United States	$0.17	500 g	97%
Chemscene	United States	$0.18	500 g	—
Ambeed, Inc.	United States	$0.18	500 g	98%
MedChemExpress MCE	Sweden	$0.22	500 g	—
Fluorochem EU	Germany	$0.38	100 g	97%
ALFA AESAR	Germany	$0.38	500 g	99%
AstaTech, Inc	United States	$0.39	100 g	95%
AK Scientific, Inc.	United States	$0.54	100 g	99%
Angene International Limited	United States	$1.31	100 g	99%
TargetMol Chemicals	China → United States	$35.00	1 g	99.59%
Labotest KG	Germany	$453.00	1000 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	97%

Chemical Identity

CAS78-27-3

PubChem CID6525

DTXSIDDTXSID0021757

FormulaC8H12O

Mol. Weight124.18 g/mol

SMILESC#CC1(CCCCC1)O

Data Sources

EPA CompTox (DSSTox) · DTXSID0021757Retrieved 2026-04-06
PubChem · compound 6525Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1-Ethynylcyclohexanol (CAS 78-27-3) https://chemicalindependence.com/chemical/78-27-3/ EPA CompTox (DSSTox): DTXSID0021757. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0021757 PubChem: 6525. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6525 EPA Chemical Data Reporting: 78-27-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 78-27-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290619 for CAS 78-27-3. Reporting year: 2024. https://usatrade.census.gov/