9-Octadecenoic acid, 12-hydroxy-, 3-hydroxy-2,2-bis(hydroxymethyl)propyl ester, (9Z,12R)-

CAS 78-22-8

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$81M

Top sourceChina 35%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291819 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291819, which covers 96 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 35%ChinaIN 34%IndiaIT 9%ItalyDE 9%GermanyJP 4%Japan

Switzerland
Ukraine
Colombia
Taiwan
Belgium
Israel
Sweden
Hungary
Ireland
Slovakia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Aurorium

Why It Matters

Sectors

Paints & Coatings

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Diluent in Paint and Coating Manufacturing (90%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS78-22-8

PubChem CID6912076

DTXSIDDTXSID90883223

FormulaC23H44O6

Mol. Weight416.6 g/mol

SMILESCCCCCCC(CC=CCCCCCCCC(=O)OCC(CO)(CO)CO)O

Data Sources

EPA CompTox (DSSTox) · DTXSID90883223Retrieved 2026-04-06
PubChem · compound 6912076Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

9-Octadecenoic acid, 12-hydroxy-, 3-hydroxy-2,2-bis(hydroxymethyl)propyl ester, (9Z,12R)- (CAS 78-22-8) https://chemicalindependence.com/chemical/78-22-8/ EPA CompTox (DSSTox): DTXSID90883223. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID90883223 PubChem: 6912076. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6912076 EPA Chemical Data Reporting: 78-22-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 78-22-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291819 for CAS 78-22-8. Reporting year: 2024. https://usatrade.census.gov/