Water
Drug ingredientActive ShortageCAS 7732-18-5
This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$154M
Top sourceGermany 55%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 285390 · basket
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 285390, which covers 46 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
DE 55%GermanyCA 21%CanadaJP 6%JapanGB 4%United KingdomKR 3%South Korea
- Spain
- Taiwan
- Netherlands
- Philippines
- Sweden
- El Salvador
- Singapore
- Belgium
- Brazil
- Austria
- Israel
- Czech Republic
- Slovakia
- Dominican Republic
- Guyana
- Argentina
- Hong Kong
- Indonesia
- Colombia
EPA-registered manufacturers (1)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Brenntag
Domestic parents -- activity not disclosed (3)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Blue Tree Holdings
Polyventive
Shinhung Global U.S.A
EPA-registered importers (1)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Tribute Energy
91 FDA-registered drug labelers
A-S Medication Solutions
Acme United Corporation
Aero Healthcare US LLC
American Regent, Inc.
ANUBIS COSMETICS SL
Apex Energetics Inc.
AQBC CO., LTD
Asclemed USA, Inc.
Aspen Notre Dame De Bondeville
B. Braun Medical Inc.
Bausch & Lomb Incorporated
Bavarian Nordic A/S
Baxter Healthcare Company
Baxter Healthcare Corporation
Becton Dickinson and Company
Bestmade Natural Products
BioActive Nutritional, Inc.
Biocon Biologics Inc.
Cardinal Health
Cardinal Health 107, LLC
Chain Drug Marketing Assoc., Inc.
Chartwell RX, LLC
Cintas Corporation
Civica, Inc.
CMC Group Inc.
Crane Safety LLC
CVS Pharmacy
Deseret Biologicals, Inc.
DNA Labs, Inc.
Dr.Reddy's Laboratories Inc.,
Dynamic Safety International
ECOLAB Food Safety Specialties, Inc.
Eli Lilly and Company
Encon Safety Products, Inc.
Energique, Inc.
Eyes-Plus LLC
Fresenius Kabi USA, LLC
Fujian Genohope Biotech Ltd.
Global Equipment Company
Guanghzou AiXin Biotech Co Ltd
Guangzhou Ariel Biotech Co., Ltd.
Guangzhou shangwei Beauty TechnologyCo.,Ltd.
HART Health
Haws Corporation
Henry Schein, Inc.
HF Acquisition Co LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
Honeywell Safety Products USA, Inc.
Honeywell Safety Products, Inc.
Hospira, Inc.
Huanggang Vicom Medical Supplies Co., Ltd.
Hubei Changjian Medical Products Co., Ltd.
ICU Medical Inc.
INNOVATIVE SAFETY SUPPLY INC.
Isomedix Operations Inc.
Jiangxi Zhenmei Biological Technology Co.,Ltd
KC Pharmaceuticals, Inc.
Klosterfrau Berlin GmbH
Kroger Company
LABORATORIOS GRIFOLS SA
M-star (Hubei) Health&Care Products Co., Ltd.
McKesson
Medefil, Inc.
Medical Purchasing Solutions, LLC
Merck Sharp & Dohme LLC
Miracle Eye Pharmaceuticals
Nelson Bach USA Limited
Nephron Pharmaceuticals Corporation
Niagara Pharmaceuticals Inc.
Novo Nordisk
Novo Nordisk Production Belgium SA
Opalshi(Guangzhou)E-commerce Co. Ltd.
Optics Laboratory Inc.
ParaDocs All Natural, Inc.
Patheon Manufacturing Services LLC
ProPharma Distribution
Rite Aid
Rite Aid Corporation
RIVIERA PHARMA INC
ROVI Pharma Industrial Services S.A.
Rugby Laboratories
Sandoz Inc
Shenzhen Yagao Technology Co., Ltd.
Siddha Flower Essences LLC
Siegfried Hameln GmbH
Tender Corporation
Thompson Safety
Uline.
Unifirst First Aid Corporation
United Therapeutics Corporation
Walgreens
Why It Matters
Sectors
HealthMetals & Mining
Downstream Uses
Appears in 76 drug and cosmetic product listings (FDA).
- •Sterile Water
- •Thompson Safety Eyewash
- •Anubis Barcelona Regul Oil
- •Anubismed
- •Medics Choice Soothing Eye Wash
- •Uline Eyewash
- •Eye Wash
- •Anubis Barcelona New Even
Show all 76
- •Quality Choice Eye Wash
- •Plaque identifying
- •PhysiciansCare Ophthalmic Solution Eyewash
- •Ocufresh
- •Bacteriostatic Water
- •Anubis Barcelona
- •Xpect Eyewash
- •Bio Rock Water
- •Green Guard First Aid Eye Wash
- •Eye Clean
- •T-27
- •PUR-WASH
- •teeth and gums
- •Dynamic Eyewash with Eyecup
- •Kollourion Eyesalve Eyewash
- •Anubis Barcelona Vital Line
- •Suntan
- •Sterile Diluent
- •GI Drainage
- •Medi-First First Aid Eye Wash
- •Eyewash Additive Concentrate
- •Fendall Pure Flow
- •Rehydrate Jr.
- •lung and sinus
- •Bestmade Natural Products BM63
- •Anubis Barcelona Protective Line
- •2-Pack Facial Serum
- •Sterile Diluent for Treprostinil
- •Easy Care First Aid Eyewash
- •AeroWash Eyewash
- •Bach Original Flower Remedies Rock Water
- •F02 ANGR-FLX
- •F09 LTGO
- •Leader Eye Wash
- •Tinted Sunscreen Foundation
- •Rite Aid Eye Wash
- •Advanced Eye Relief Eye Wash
- •Multi Flower
- •Firstep Firstflush
- •Ecolab Eye Wash
- •Insulin Diluting Medium FOR Kirsty
- •Eyes Alive Eye Wash
- •Huanggang Eye Wash
- •CheBoho TEA TREE ACNE
- •PEMF Optimizer
- •Bach Original Flower Remedies
- •Sterile Diluent for Remodulin
- •Eyesaline Emergency Eyewash
- •Eyesaline Eyewash Concentrate
- •Dangtteol
- •PhysiciansCare Ophthalmic Solution Eyewash Purified Water, 98.3%
- •Physicians Care Eyewash
- •Insulin Diluting Medium for NovoLog
- •Empathy
- •Medi-First Plus First Aid Eye Wash
- •Diluent Component
- •Rehydrate
- •EyS Eye Wash
- •Plus Rinse Emergency Eyewash
- •Crane Safety Eye Wash
- •Anubis Barcelona Spa Line
- •Anubis Barcelona Total Hydrating
- •Diluent
- •Rugby EYE WASH
- •Walgreens Sterile Soothing Eye Wash
- •pH Neutral Emergency Eyewash
- •Fendall 2000 Pure Flow
- •Bestmade Natural Products Field of Flowers Formula
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
Active Shortage
Shortage History
Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.
- Current shortage
Sterile Water Irrigant
Shortage listed since April 28, 2023
Manufacturer reports: 1 unavailable, 1 limited, 1 available
- Current shortage
Sterile Water Injection
Shortage listed since November 23, 2021
Manufacturer reports: 2 limited, 1 available
Industrial Uses
Used in 3 sectors as 4 functional roles.
- •Anti-adhesive agents in Wood Product ManufacturingProcessing—incorporation into article
- •Lubricants and lubricant additives in Petroleum Lubricating Oil and Grease Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Sealant (barrier) in ConstructionUse—non-incorporative activities
- •Adhesives and sealant chemicals in ConstructionUse—non-incorporative activities
Vendor Pricing
$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$7.00 / 500 g
PurityNot recorded
Vendors8 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
7 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $0.02 | 500 g | — |
| Fulfilled by Molport | Latvia | $0.20 | 25 g | — |
| Sigma-Aldrich (Rush Stock) | Germany | $3.55 | 100 g | — |
| Sigma-Aldrich | Germany | $3.55 | 100 g | — |
| A2B Chem LLC | United States | $44.00 | 25 g | — |
| AA BLOCKS | United States | $49.20 | 25 g | — |
| Angene | China → Hong Kong | $4266.67 | 30 mg | — |
Chemical Identity
CAS7732-18-5
PubChem CID962
DTXSIDDTXSID6026296
FormulaH2O
Mol. Weight18.015 g/mol
SMILESO
Data Sources
- EPA CompTox (DSSTox) · DTXSID6026296Retrieved 2026-04-06
- PubChem · compound 962Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA Drug ShortagesRetrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Water (CAS 7732-18-5) https://chemicalindependence.com/chemical/7732-18-5/ EPA CompTox (DSSTox): DTXSID6026296. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6026296 PubChem: 962. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/962 EPA Chemical Data Reporting: 7732-18-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA Drug Shortages: CAS 7732-18-5. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 285390 for CAS 7732-18-5. Reporting year: 2024. https://usatrade.census.gov/