Barium sulfate
Drug ingredientCAS 7727-43-7
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$228M
Top sourceIndia 21%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 251110, 283327 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
IN 21%IndiaCN 18%ChinaMA 17%MoroccoMX 17%MexicoLA 9%Laos
- Pakistan
- Turkey
- Canada
- United Kingdom
- Spain
- Malaysia
- South Africa
- Hong Kong
EPA-registered manufacturers (3)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Rio Tinto Plc · GB United Kingdom
Minerals Technologies
Rio Tinto America
Domestic parents -- activity not disclosed (6)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Aalborz Chemical
Azelis Americas Case
Cataler North America
Cirba Solutions
Seppic
Show all 6
Wilbur-Ellis Holdings Ii
EPA-registered importers (25)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Dksh Canada · CA Canada
Heubach Holdings Sarl · LU Luxembourg
Sakai Trading · JP Japan
Sika Ag · CH Switzerland
Show all 25
Venator Materials Plc · GB United Kingdom
Advanced Micronutrient Products
Aoc
Axxess International
Basf
Blachford
Clarios
General Electric Co (Ge Co)
Hct
Hempel Usa
Lanxess
Nippon Paint Automotive Americas
Sakai Trading New York
Shinhung Global U.S.A
Sika
Target
Tenneco Brake
The Sherwin Williams
Valudor Products
Venator Materials
3 FDA-registered drug labelers
CIMBAR PERFORMANCE MINERALS, INC.
E-Z-EM Canada Inc
E-Z-EM, INC.
Why It Matters
Sectors
HealthAgricultureEnergyWaterElectronicsTransportationConstructionMetals & MiningPlastics & RubberTextilesConsumer ProductsPaints & CoatingsPaper & PrintingCore Chemicals
Downstream Uses
Appears in 16 drug and cosmetic product listings (FDA).
- •Varibar Nectar
- •Varibar Honey
- •Readi-Cat 2 Mochaccino Smoothie
- •Varibar Pudding
- •Readi-Cat 2 Banana Smoothie
- •E-Z-Paque
- •Entero Vu 24%
- •Varibar Thin Liquid
Show all 16
- •Readi-Cat 2 Berry Smoothie
- •Varibar Thin Honey
- •E-Z-HD
- •Readi-Cat 2
- •E-Z-Paste
- •E-Z-Disk
- •Tagitol V
- •Readi-Cat 2 Creamy Vanilla Smoothie
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 19 sectors as 9 functional roles.
- •Swelling agent in Electrical Equipment, Appliance, and Component Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Plastics Product Manufacturing (40%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Plastics Product Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Transportation Equipment Manufacturing (50%)Processing—incorporation into article
- •Filler in All Other Chemical Product and Preparation Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Plastics Material and Resin Manufacturing (45%)Processing—incorporation into formulation, mixture, or reaction product
- •Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Construction (20%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Miscellaneous ManufacturingProcessing—incorporation into article
- •Filler in Electrical Equipment, Appliance, and Component ManufacturingProcessing—incorporation into article
- •Filler in Machinery ManufacturingProcessing—incorporation into article
- •Filler in Furniture and Related Product ManufacturingProcessing—incorporation into article
- •Filler in Miscellaneous ManufacturingProcessing—incorporation into article
- •Filler in Wood Product ManufacturingProcessing—incorporation into article
- •Intermediate in All Other Basic Inorganic Chemical Manufacturing (0%)Processing as a reactant
- •Catalyst in Transportation Equipment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Synthetic Rubber Manufacturing (33%)Processing—incorporation into formulation, mixture, or reaction product
- •Dye in Printing and Related Support Activities (100%)Use—non-incorporative activities
- •Binder in Primary Metal Manufacturing (100%)Processing—incorporation into article
- •Filler in ConstructionUse—non-incorporative activities
- •Filler in Utilities (95%)Processing—incorporation into article
- •Filler in Oil and Gas Drilling, Extraction, and Support activities (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Flame retardant in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Pigment in Transportation Equipment ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
Chemical Identity
CAS7727-43-7
PubChem CID24414
DTXSIDDTXSID0050471
FormulaBaO4S
Mol. Weight233.39 g/mol
SMILES[O-]S(=O)(=O)[O-].[Ba+2]
Data Sources
- EPA CompTox (DSSTox) · DTXSID0050471Retrieved 2026-04-06
- PubChem · compound 24414Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Barium sulfate (CAS 7727-43-7) https://chemicalindependence.com/chemical/7727-43-7/ EPA CompTox (DSSTox): DTXSID0050471. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0050471 PubChem: 24414. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/24414 EPA Chemical Data Reporting: 7727-43-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 7727-43-7. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 251110,283327 for CAS 7727-43-7. Reporting year: 2024. https://usatrade.census.gov/