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Tetrasodium pyrophosphate

Drug ingredient

CAS 7722-88-5

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 7722-88-5
4 Na⁺
US productionCBI
Import value, 2024$95M
Top sourceCanada 30%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 283539 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 283539, which covers 21 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CA 30%CanadaDE 19%GermanyMY 17%MalaysiaCN 13%ChinaIT 9%Italy
EPA-registered manufacturers (3)
Macdermid
Minerals Technologies
Prayon
Domestic parents -- activity not disclosed (2)
Icl Specialty Products North America
Wintersun International
EPA-registered importers (7)
Geschwister Oetker Beteiligungen Kg · DE Germany
Basstech International
Budenheim Usa
Chemical Distribution Network
Global Chemical Resources
Show all 7
Innophos Incorporated
W. R. Grace & Co. - Conn.

Why It Matters

Sectors
HealthFoodEnergyConstructionMetals & MiningConsumer ProductsCore Chemicals
Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

  • •Technescan PYP
  • •Denti Buongiorno Plaque CARE Lemon MINT Tooth
  • •Mimibo Premium Tooth
  • •Onetoothclinic Tooth
  • •Denti Buongiorno Plaque CARE Tooth
  • •V34 Colour Corrector
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 10 sectors as 14 functional roles.

  • •Emulsifier in Food, beverage, and tobacco product manufacturing (80%)Processing—incorporation into formulation, mixture, or reaction product
  • •Flocculating agent in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Chelating agent in Fabricated Metal Product Manufacturing (33%)Processing—incorporation into formulation, mixture, or reaction product
  • •Dispersing agent in Oil and Gas Drilling, Extraction, and Support activities (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Abrasives in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Dispersing agent in Food, beverage, and tobacco product manufacturing (40%)Processing—incorporation into formulation, mixture, or reaction product
  • •Thickening agent in Food, beverage, and tobacco product manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Chelating agent in Food, beverage, and tobacco product manufacturing (80%)Processing—incorporation into formulation, mixture, or reaction product
  • •Deflocculant in Mining (except Oil and Gas) and support activities (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Binder in Primary Metal Manufacturing (100%)Processing—incorporation into article
  • •Corrosion inhibitor in Miscellaneous ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Antioxidant in Miscellaneous ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Absorbent in Industrial Gas Manufacturing (100%)Use—non-incorporative activities

Chemical Identity

CAS7722-88-5
PubChem CID24403
DTXSIDDTXSID9042465
FormulaNa4O7P2
Mol. Weight265.9 g/mol
SMILES[O-]P(=O)([O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]

Data Sources

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Brief citations

Tetrasodium pyrophosphate (CAS 7722-88-5) https://chemicalindependence.com/chemical/7722-88-5/ EPA CompTox (DSSTox): DTXSID9042465. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9042465 PubChem: 24403. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/24403 EPA Chemical Data Reporting: 7722-88-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 7722-88-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 283539 for CAS 7722-88-5. Reporting year: 2024. https://usatrade.census.gov/