Nickel chloride

Drug ingredient

CAS 7718-54-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US production1.7M lb

Import value, 2024$2M

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceItaly 46%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 282735 · exact

EPA reports by year

2023: US production 1.7M lb · Imports Confidential
2019: US production 839.9K lb · Imports 468.0K lb

Source Countries

Country of origin for US imports, from Census customs data (2024).

IT 46%ItalyTW 39%TaiwanDE 10%GermanyHK 2%Hong KongCA 1%Canada

India
China

EPA-registered manufacturers (3)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Umicore Sv · BE Belgium

Umciore Usa

Univertical

EPA-registered importers (3)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Umicore Sa · BE Belgium

Atotech Manufacturing

Umicore Usa

1 FDA-registered drug labeler

Hahnemann Laboratories, INC.

Why It Matters

Sectors

HealthElectronicsTransportationPaints & CoatingsCore Chemicals

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Niccolum Muriaticum

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 5 sectors as 1 functional role.

•Plating agent in Transportation Equipment Manufacturing (33%)Processing as a reactant
•Plating agent in Electrical Equipment, Appliance, and Component Manufacturing (33%)Processing—incorporation into article
•Plating agent in Computer and Electronic Product Manufacturing (33%)Processing as a reactant
•Plating agent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Plating agent in All Other Chemical Product and Preparation Manufacturing (66%)Processing as a reactant

Chemical Identity

CAS7718-54-9

PubChem CID24385

DTXSIDDTXSID7040316

FormulaCl2Ni

Mol. Weight129.6 g/mol

SMILESCl[Ni]Cl

Data Sources

EPA CompTox (DSSTox) · DTXSID7040316Retrieved 2026-04-06
PubChem · compound 24385Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Nickel chloride (CAS 7718-54-9) https://chemicalindependence.com/chemical/7718-54-9/ EPA CompTox (DSSTox): DTXSID7040316. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7040316 PubChem: 24385. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/24385 EPA Chemical Data Reporting: 7718-54-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 7718-54-9. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 282735 for CAS 7718-54-9. Reporting year: 2024. https://usatrade.census.gov/