Citric acid
Drug ingredientThis drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US ProductionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import Value$399M
Top SourceCanada 49%
The EPA did not publish how much of this chemical companies made or imported, or marked that amount confidential. Without that volume, ACID cannot calculate import dependency.
Where It Comes From
Customs basis: HS 291814 · exact
Source Countries
Country of origin for US imports, from Census customs data (2023).
CA 49%CanadaMY 35%MalaysiaCO 8%ColombiaCN 2%ChinaTR 2%Turkey
- Germany
- Taiwan
- Italy
- Spain
- Georgia
- Israel
- Pakistan
- Japan
- United Kingdom
- Australia
- Jordan
- Lithuania
- Netherlands
- Lebanon
- Egypt
- Chile
- Vietnam
- Switzerland
- South Korea
- Serbia
- Bahamas
EPA-registered manufacturers (5)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Ter Hell & Co Gmbh · DE Germany
Archer Daniels Midland
Cargill, Incorporated
Gehring-Montgomery
Tate & Lyle Ingredients Americas
EPA-registered importers (35)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Industrias Alen S A De C V · MX Mexico
Jungbunzlauer Holding Ag · CH Switzerland
Perstorp Ab · SE Sweden
Rudolf Gmbh · DE Germany
Show all 35
Albemarle
Alen Usa
Avantor
Basf
Brenntag
Brown Chemical
Cataler North America
Delta Carbona
Diversey
Emd Holding
Greenchem Industries
Harcros Chemicals
Ideal Chemical & Supply
Industrial Chemicals
Jungbunzlauer
Kemira Chemicals
Kg International
Kic Chemicals
Perstorp Polyols
Pressure Vessel Service
Reckitt Benckiser
Rudolf Venture Chemical
Solvchem
Target
Tate & Lyle Ingredients Americas
The Procter & Gamble
Uzin Utz
Valagro Usa
Valudor Products
Wintersun International
1 FDA-registered drug labeler
Nanjing Hongruixing Biological Technology Co., Ltd
Why It Matters
Sectors
FoodPlastics & RubberPaints & CoatingsPaper & PrintingCore ChemicalsHealthEnergyConsumer ProductsMetals & MiningWaterTextilesAgricultureConstruction
Downstream Uses
Appears in 74 drug and cosmetic product listings (FDA).
- •Swiss BLEU Relief-Calm Antimicrobial Skin Cream
- •ACD-A
- •CPDA-1
- •Anticoagulant Citrate Dextrose A
- •FCS CP
- •Glucoreg
- •Top Value Effervescent Pain Relief
- •Sodium Citrate and Citric Acid
Show all 74
- •CitriPlus
- •Quality Choice Effervescent Antacid and Pain Relief
- •HZ-Chord
- •Aller-Chord F
- •Category V
- •Walgreens Antacid Pain Relief Extra Strength
- •ACD Blood-Pack Units (PL 146 Plastic)
- •Kroger Effervescent Antacid and Pain Relief
- •FCS HP
- •Bio Co-Enzyme Phase
- •Mitochondria PRO
- •AnubisMed
- •Up and Up Antacid and Pain Relief
- •Rite Aid Antacid and Pain Relief
- •Teruflex Blood with Diversion Blood Sampling Arm 70 mL CPDA-1
- •A12 DTX-Kidney
- •XS H2O Liquescence
- •REFL HS
- •Good Sense Effervescent Antacid and Pain Relief
- •teruflex blood bag system with diversion blood sampling arm 70 ml cpda-1
- •Clenpiq
- •Lyme and Co-Infection Nosode
- •Alka-Seltzer Extra Strength
- •Alka-Seltzer Original
- •Endocrinpath
- •Leader Extra Strength Effervescent Antacid and Pain Reliever
- •Anticoagulant Citrate Phosphate Dextrose (CPD) Blood-Pack Units in PL 146 Plastic
- •Liverex I
- •Herbal Diuretic Liquescence 3011
- •Best Choice Effervescent Antacid Pain Relief
- •Isopathic Phenolic Rings
- •Spleenex V
- •Alka Seltzer Originial 1s Blister Pack
- •Alka-Seltzer
- •Care One Original Antacid and Pain Relief
- •Kidnex IV
- •Teruflex Blood Anticoagulant Citrate Phosphate Dextrose Adenine (CPDA-1) for Collection of 450mL of Blood
- •Hepatic-Tone
- •WinCo Foods Effervescent Antacid and Pain Relief
- •Equate Effervescent Antacid and Pain Relief
- •Bromo Seltzer
- •Market Basket Effervescent Antacid and Pain Relief
- •Publix Fast Relief Effervescent
- •Alka-Seltzer Heartburn and Pain
- •Adaptopath
- •Renacidin
- •Walgreens Effervescent Pain Relief
- •CVS Health Antacid and Pain Reliever
- •E-Z-GAS II
- •Signature Care Effervescent Antacid and Pain Relief
- •HEB Extra Strength Effervescent Antacid and Pain Relief
- •Meijer Effervescent Antacid and Pain Relief
- •Spleenex VH
- •Drug Mart Effervescent Pain Relief
- •Cell Energy Performance Drops 2048
- •Quality Choice Extra Strength Effervescent Antacid and Pain Relief
- •Metab
- •TopCare Effervescent Antacid and Pain Relief
- •Effervescent Antacid and Pain Relief
- •Equaline Effervescent Antacid and Pain Relief
- •DG Health Effervescent Antacid and Pain Relief
- •LY-CO
- •Metab 6012
- •A01 Cellular Recharge
- •N03 Exchem
- •CVS Health Extra Strength Antacid and Pain Reliever
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 16 sectors as 19 functional roles.
- •pH regulating agent in Wholesale and Retail Trade (100%)Use—non-incorporative activities
- •Surface modifier in Fabricated Metal Product Manufacturing (0%)Processing—incorporation into article
- •Aerating and deaerating agents in ConstructionProcessing—incorporation into article
- •Surfactant (surface active agent) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Defoamer in Paint and Coating Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Opacifer in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Other (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Defoamer in Food, beverage, and tobacco product manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Defoamer in Paper Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Plastics Material and Resin Manufacturing (1%)Processing as a reactant
- •Agricultural chemicals (non-pesticidal) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (3%)Processing—incorporation into formulation, mixture, or reaction product
- •Paint additives and coating additives not described by other categories in Paint and Coating Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agents and surface treating agents in Primary Metal Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Process regulators in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Laboratory chemicals in All Other Chemical Product and Preparation ManufacturingProcessing—repackaging
- •Flocculating agent in Paper Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Agricultural chemicals (non-pesticidal) in Agriculture, Forestry, Fishing and Hunting (100%)Processing as a reactant
- •Adhesives and sealant chemicals in Oil and Gas Drilling, Extraction, and Support activities (1%)Processing as a reactant
- •Corrosion inhibitors and anti-scaling agents in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvents (which become part of product formulation or mixture) in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (32%)Processing—incorporation into formulation, mixture, or reaction product
- •Surface active agents in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (4%)Processing—incorporation into formulation, mixture, or reaction product
- •Lubricants and lubricant additives in All Other Chemical Product and Preparation Manufacturing (3%)Processing—incorporation into formulation, mixture, or reaction product
- •Oxidizing/reducing agents in Textiles, apparel, and leather manufacturing (12%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
Chemical Identity
CAS77-92-9
PubChem CID311
DTXSIDDTXSID3020332
FormulaC6H8O7
Mol. Weight192.12 g/mol
SMILESC(C(=O)O)C(CC(=O)O)(C(=O)O)O
Data Sources
DTXSID30203322026-04-06
https://doi.org/10.23645/epacomptox.5588566
Archive: data/sources/comptox/dsstox_identifiers.csv
3112026-04-06
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/311/property/MolecularFormula,MolecularWeight,CanonicalSMILES,InChIKey/JSON
Archive: data/sources/pubchem_properties/311.json
77-92-92026-04-24
https://www.epa.gov/chemical-data-reporting
Archive: data/sources/epa_cdr/2020_cdr.csv
CAS 77-92-92026-04-07
https://open.fda.gov/data/ndc/
Archive: data/sources/fda/ndc/ndc.json