Chlorthalidone

Drug ingredient

CAS 77-36-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 77-36-1
US productionNot reported
Import value, 2024$2.0B
Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland
52 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Ajanta Pharma USA Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Amneal Pharmaceuticals LLC
Amoli Organics (A Division of Umedica Laboratories Pvt.Ltd.)
ANI Pharmaceuticals, Inc.
Aphena Pharma Solutions - Tennessee, LLC
Ascend Laboratories, LLC
AvPAK
Azurity Pharmaceuticals, Inc. (formerly Arbor Pharmaceuticals)
Bryant Ranch Prepack
Casper Pharma LLC
Chartwell RX, LLC
Chromo Laboratories India Private Limited
Coupler LLC
CTX Lifesciences Pvt. Ltd.
Curia Italy S.r.l.
Direct_Rx
Dr. Reddy's Laboratories Inc.
Honour Lab Limited
Ingenus Pharmaceuticals, LLC
Ipca Laboratories Limited
JUBILANT CADISTA PHARMACEUTICALS,INC.
Lifestar Pharma LLC
Maithri Drugs Private Limited
Major Pharmaceuticals
MARLEX PHARMACEUTICALS, INC
MSN Life Sciences Private Limited
Mylan Institutional Inc.
Mylan Pharmaceuticals Inc.
Nivagen Pharmaceuticals, INC.
Northstar Rx LLC.
Northwind Health Company, LLC
PD-Rx Pharmaceuticals, Inc.
Pharma Packaging Solutions, LLC dba Tjoapack LLC
Preferred Pharmaceuticals Inc.
Proficient Rx LP
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Safecor Health, LLC
Sun Pharmaceutical Industries, Inc.
TAGI Pharma, Inc.
Takeda Ireland Limited
Takeda Pharmaceutical Co LTD
Unichem Laboratories Limited, India
Unichem Pharmaceuticals (USA), Inc.
Upsher-Smith Laboratories, LLC
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •Chlorthalidone
  • •Atenolol AND Chlorthalidone
  • •Chlorthalidone Chlorthalidone
  • •Thalitone
  • •Tenoretic
  • •Hemiclor
  • •Edarbyclor
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$2.50/gCombi-Blocks, Inc.
CountryUnited States
Pack$250.00 / 100 g
Purity97%
Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS77-36-1
PubChem CID2732
DTXSIDDTXSID4022812
FormulaC14H11ClN2O4S
Mol. Weight338.8 g/mol
SMILESC1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O

Data Sources

Brief citations

Chlorthalidone (CAS 77-36-1) https://chemicalindependence.com/chemical/77-36-1/ PubChem: 2732. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/2732 FDA National Drug Code directory: CAS 77-36-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 77-36-1. Reporting year: 2024. https://usatrade.census.gov/