Sodium fluoride
Drug ingredientCAS 7681-49-4
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US production303.7K lb
Import value, 2024$43M
Import volume4.4M lb
Import dependency94%
Top sourceChina 35%
Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 282619 · basket
EPA reports by year
- 2023
- US production 303.7K lb · Imports 4.4M lb
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 282619, which covers 35 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 35%ChinaDE 25%GermanyJP 21%JapanIN 10%IndiaTW 6%Taiwan
- Singapore
- United Kingdom
- South Korea
- South Africa
- Liechtenstein
- Switzerland
- Russia
- Netherlands
- Italy
- Belgium
- Mexico
- Indonesia
- Hong Kong
EPA-registered manufacturers (2)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Macdermid
Shinagawa Americas
Domestic parents -- activity not disclosed (2)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Chemical Distribution Network
Harcros Chemicals
EPA-registered importers (7)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Brenntag
Cascade Columbia
Chemalloy
Lowe Chemical
Phibro Animal Health
Show all 7
Water Solutions Un
Wego Chemical Group
185 FDA-registered drug labelers
9055-7588 Qubec Inc. DBA ATTITUDE
9055-7588 Quebec Inc. DBA Attitude
A PLUS MERCHANDISE LLC
A-S Medication Solutions
Access Business Group LLC
Accupac LLC
Amazon.com Services LLC
AMD Medicom
American Sales
Apex Energetics Inc.
ASHTEL STUDIOS, INC
ATOMY CO., LTD.
ATOSAFE CO., Ltd
Auraglow LLC
Avespan LLC
AvKARE
AvPAK
Benco Dental
Beyond International Inc
Big Lots Stores, Inc.
BioActive Nutritional, Inc.
Bob Barker Company Inc.
BonGeo Pharmaceuticals, Inc.
Bryant Ranch Prepack
Burel Pharmaceuticals LLC
Burkhart Dental Supply Inc
Caldwell Consumer Health LLC
Caldwell Health LLC
CarWin Pharmaceutical Associates, LLC
CHAIN DRUG MARKETING ASSOCIATION INC
Chattem, Inc.
Church & Dwight Co., Inc.
Colgate Oral Pharmaceuticals, Inc.
COLGATE PALMOLIVE COMPANY
Colgate-Palmolive
Colgate-Palmolive - do not use
CREDENTIS AG
Crosstex International Inc.
CVS
CVS Pharmacy
CVS Pharmacy, Inc.
Cypress Pharmaceutical, Inc.
Darby Dental Supply, LLC
Demoulas Super Markets, Inc
DEN-MAT HOLDINGS, LLC.
DENT-MAT HOLDINGS, LLC.
DENTAL ALLIANCE HOLDINGS LLC
Dental Technologies, Inc.
Dentisse, Inc.
Deseret Biologicals, Inc.
Dharma Research, Inc.
DMG AMERICA, LLC
DOCSMEDI Co., Ltd.
Dolgencorp, LLC
DONG IL PHARMS CO., LTD.
Dr Jen Natural, LLC
Dr. G. H. Tichenor's Antiseptic Company
DUKAL LLC
Dynarex Corporation
Elevate Oral Care
EMAG AG
Energetix Corporation
Family Dollar (FAMILY WELLNESS)
Family Dollar Stores, Inc
Farmasi US LLC
Fulijaya Manufacturing Sdn. Bhd
GC America Inc.
Geri-Gentle Corporation
GURUNANDA, LLC
H E B
Hahnemann Laboratories, INC.
Haleon US Holdings LLC
HARRIS TEETER
Henry Schein
Henry Schein, Inc.
HISMILE PTY LTD
IPG PHARMACEUTICALS, INC.
J.M. Murray Center Inc.
Jiangxi Dentalbright Technology Co., Ltd
Kaylaan LLC
Kenvue Brands LLC
Kingkey MBC Life Technology Group Co.,Ltd
Kroger
Kroger Company
LAMOIYAN CORPORATION
Lander Enterprises, LLC
LEC Custom Products, Inc.
LG H&H CO., LTD.
LG HOUSEHOLD & HEALTH CARE LTD.
Lidl US, LLC
Lornamead
Lornamead Products
MADE BY DENTISTS INC
Massco Dental A Division of Dunagin Pharmaceuticals
McKesson
Meijer Distribution Inc
Meijer, Inc.
Melaleuca, Inc
Merck KGaA
Method Pharmaceuticals, LLC
Mission Hills S.A de C.V
MKJ BRANDS LLC
Moon Oral Care LLC
Mycone Dental Supply Co., Inc DBA Keystone Industries and Deepak Products Inc
Navajo Manufacturing Company Inc
New World Imports, Inc
Nice-Pak Products, LLC
Nutriplant Industria e Comrcio S.A.
Nutritional Specialties, Inc.
O&M HALYARD, INC.
Old East Main CO.
Oxyfresh Worldwide Inc
Paranmare LLC
Pascal Company, Inc.
Peer Pharm Ltd.
PERIOSCIENCES LLC
POPONSMILES,LLC
Prime Tooth Care LLC
Procter & Gamble Manfuacturing Company
Procter & Gamble Manufactura, S. de R.L. de C.V.
Procter & Gamble Manufacturing Company
Procter & Gamble Manufacturing Mxico, S. de R.L. de C.V.
Professional Complementary Health Formulas
Protegera, Inc
Publix Super Market
Publix Super Market Inc
Publix Super Markets, Inc.
PureLife Dental
PureTek Corporation
Quip NYC Inc.
Rabbit Indstria e Comrcio de Produtos de Higiene Pessoal Ltda
Ranir LLC
Retail Business Services, LLC
Rising Pharma Holdings, Inc.
Rite Aid
Rite Aid Corporation
Ross Healthcare Inc.
Rowpar Pharmaceuticals, Inc.
Safco Dental Supply LLC
Safeway
Sheffield Pharmaceuticals LLC
Solventum US LLC
SPARROW LIFE CARE PRIVATE LIMITED
Spectrum Laboratory Products, Inc.
SUNLIT FLUO & CHEMICAL CO., L TD. CHUNG-LI FACTORY
SuperMouth, LLC.
TAI GUK PHARM. CO., LTD
Tai Guk Pharma. Co., Ltd.
Target
TARGET CORPORATION
The Atlanta Dental Supply Company DBA Advanced Dental Products
The Kroger Co.
The Procter & Gamble Manufacturing Company
Tiger Supply Inc
TJA Health LLC
Tom's of Maine
Tom's of Maine, Inc.
Top Quality Manufacturing, Inc.
TOPCO Assoc. LLC
Topco Associates LLC
TRADER JOE'S COMPANY
Twice Twice LLC
Ultradent Products, Inc
United Natural Foods, Inc. dba UNFI
Universal Distribution Center LLC
Valu Merchandisers Company
Wal-Mart Stores Inc
Walgreen Co.
Walgreens
Walmart
Walmart Inc.
Westminster Pharmaceuticals, LLC
WHITE GLO USA INC
Willo 32 Inc
WINDER LABORATORIES, LLC
WORLD DENTISTS ASSOCIATION AMERICA LIMITED
Wuhan Zonsen Medical Products Co., Ltd.
Xiling (Zhenjiang) Medical Technology Co., Ltd.
Xlear Inc.
Yangzhou Hongshengding Chemical Co.,Ltd.
Yangzhou ONE & ONLY Personal Care Products Co., LTD
Young Dental Manufacturing Co 1, LLC
YOUNG PS ACQUISITION, LLC
Your Military Exchanges
ZOHAR KOSHER LIMITED
Why It Matters
Sectors
HealthWaterMetals & MiningCore Chemicals
Downstream Uses
Appears in 732 drug and cosmetic product listings (FDA).
- •Acclean Foam Fluoride 60 Second Application
- •dentalux Kids ANTI-Cavity Fluoride Bubble Gum
- •Anticavity Fluoride Rinse
- •Oral Antivavity
- •Tri-Vite Drops with Fluoride
- •Anticavity
- •Brush Buddies Crayola Anticavity Fluoride Watermelon
- •Brush Buddies Mouthwash Frozen Blizzard Berry
Show all 732
- •Brush Buddies Mouthwash Disney Princesses Grand Grape
- •Unpaste
- •Made By Dentists, Inc. Whitening
- •Made by Dentists For Kids Eyeball Juice (Watermelon)
- •Doctrust ONE S Tooth
- •Freshen Up
- •Moon Whitening Anticavity
- •AutoBrush Mint
- •Strawberry Flavor Sodium Fluoride Anticavity Toothpast
- •Blue Raspberry Flavor Sodium Fluoride Anticavity Toothpast
- •Ortho Super Mint Fluoride Mouthwash
- •4-in-1 Teeth Care Pens
- •Dentalclean Ultra Refreshing Extreme Ice Dental Gel
- •Dentalclean Dental Gel Booster Adult Use
- •Crest Deep Cleanse Cavity Defense
- •Crest Complete plus Scope Pro Advanced Freshness
- •Crest Pro-Health Sensitivity Whitening Plus Scope
- •Dr. Jen SuperPaste Nano-Hydroxyapatite
- •Plak Smacker Great White Shark Cool Berry Flavor Anti Cavity Fluoride Gel Tooth
- •AdoptaPlatoon
- •Maximum Security Anticavity Gel fresh mint flavor
- •Seavue Dental Desensitizer
- •Therabreath Overnight Chamomile Mint
- •Sodium Fluoride 5000 ppm Spearmint
- •Pronamel Repair Whitening
- •Quflora Pediatric
- •Signature Care Enamel Guard Sensitive Gentle Whitening
- •Zap APF
- •Kolorz Sixty Second Fluoride PINA Colada
- •Colgate Sensitive Whitening
- •Colgate MaxFresh Watermelon Blast
- •Hello Vitamin C Whitening
- •Hello Penguin Chill
- •Colgate Optic White Purple
- •Colgate KIDS Watermelon Flavor
- •Colgate MAX White WITH MINI Bright Strips Crystal MINT
- •Sodium Fluoride 1.1%
- •Alcohol-Free Anticavity
- •Crest Fresh and White
- •Crest 3D White Charcoal
- •Natrum Fluoratum
- •PreviDent 5000 Sensitive
- •PreviDent Fresh Mint
- •Sensodyne Pronamel mineral Boost refreshing peppermint
- •Sensodyne Pronamel Intensive Enamel Repair Extra Fresh
- •Sensodyne Clinical White Enamel Strengthening
- •Sensodyne Pronamel Kids Berry Twist
- •Sensodyne Nourish Gently Soothing
- •Sensodyne Pronamel Clinical Enamel Strength Fresh Breath
- •Alcohol Free Refreshing Mint
- •HEB Extra Whitening
- •ACT Anticavity Fluoride Kids Wild Watermelon
- •Act Total Care Anticavity Fluoride Fresh Mint
- •Care One Maximum Strength
- •Sodium Flouride
- •POP Hint Of Mint
- •Himalaya PINK SALT Purple Color Corrector plus Intensive Whitening Toothpaste
- •Burkhart
- •Burkhart Neutral pH
- •Clinpro 5000
- •equate Sensitive
- •Freshmint Premium Anticavity
- •Atomy Propolis Toothpas TE 200G
- •Floriva
- •Ionite APF
- •Anticavity Rinse
- •Whitening Tooth Polish
- •Exceed Total Care Sensitive Spearmint Tooth Polish
- •OralLine
- •Sodium Fluoride Chewable
- •Multivitamin with Fluoride
- •Crest 3D White Stain Eraser
- •Flotrex
- •Fluoridex
- •Gel 1100 Grape
- •Treatment Rinse Apple
- •MIPaste Plus Strawberry
- •BIO Spectra Attitude
- •Amalgam 6003
- •Zooby Growlin Grrrape
- •Zooby Gator Gum
- •Zooby Turtle Melon
- •Denti-Care Denti-Rinse Neutral Sodium Fluoride Oral Rinse
- •Sodium fluoride
- •Colgate Ultra Brite Advanced Whitening ALL IN ONE Clean MINT
- •Colgate Cavity Protection
- •Colgate 2 IN 1 KIDS SP Strawberry
- •Darby APF Bubble GUM
- •Iris 60 Second APF
- •PerCara Kids Bubble Gum
- •Gelato APF
- •Fluoride
- •PureLife APF
- •Sodium Fluoride 1.1% Gel
- •Sodium Fluoride 5000 PPM
- •Crest 3D White Advanced Glamorous White
- •Crest Plus Active Fresh plus Whitening Scope
- •Burts Bees Complete Multi-Care
- •Crest 3D White Ultra Vivid Mint
- •Crest Pro Health Densify Rinse
- •Kids Crest Strawberry Rush
- •Tiger Supply Inc APF
- •Brush Buddies Barbie Anticavity Fluoride - Bubble Gum Flavor
- •Brush Buddies Squishmallows Anticavity Fluoride MINT Flavor
- •Brush Buddies MY Little PONY Anticavity Fluoride
- •Denti Buongiorno Plaque CARE Lemon MINT Tooth
- •Brush Buddies Hotwheel Anticavity Fluoride Strawberry
- •Brush Buddies Brbie Anticavity Fluoride Bubblegum
- •Anticavity Fluoride
- •Made By Dentists, Inc. Total Care
- •Doctrust Doublex Tooth
- •meijer Sensitive Extra Whitening
- •Hismile
- •Ice Pop Flavor Sodium Fluoride Anticavity Toothpast
- •Ortho Super Strawberry Fluoride Mouthwash
- •Dubai Chocolate Fluoride Mouthwash
- •Dentalclean Whitening Max
- •Dentalclean Blue Diamond Alcohol Free Mouthwash
- •Dr. Jen SuperPaste Perio
- •TheraBreath Fresh Breath Anticavity Mild Mint
- •TheraBreath Anticavity
- •AIM Bubble Berry
- •Close UP Freshening with Mouthwash
- •Sodium Fluoride 5000 ppm Fruit
- •Sodium Fluoride 5000 ppm Enamel Protect
- •Colgate MaxFresh Knockout
- •Hello Dragon Dazzle Dragon Dazzle Fluoride
- •Hello Wild Strawberry
- •Colgate Enamel Strength Mouthwash
- •Colgate Junior Kids Batman Mild Bubble Fruit Fluoride
- •Colgate MaxFresh Charcoal
- •Mouth Rinse
- •Crest Tartar Protection
- •Kids Crest Cavity Protection Sparkle Fun
- •Crest Complete plus Whitening plus Scope Outlast
- •Crest Complete Multi-Benefit Plus Scope
- •Crest 3D White Brilliance
- •Crest complete plus Whitening Deep Clean
- •PreviDent 5000 Enamel Protect
- •Aquafresh Extreme Clean Whitening Action
- •Biotene Fresh Mint Original
- •Sensodyne True white
- •Sensodyne Pronamel Gentle Whitening Fresh Mint
- •Sensodyne Pronamel Active Shield Cool Mint
- •Natean Clean and Whiten
- •HEB Gleaming White Arctic Mint
- •ACT Anticavity Fluoride Arctic Blast
- •ACT Anticavity Fluoride Mint
- •ACT Restoring Anticavity Fluoride Cool Mint
- •POP Feeling Peachy
- •Himalaya PINK SALT Purple Color Corrector plus Intensive Whitening Vanilla Mint
- •Perioe POP Advanced Whitening Prebiotic Cool Mint
- •Toms of Maine Whiten Plus Deep Clean Peppermint
- •Universal Charcoal WITH ALOE VERA ANTI-Cavity Fluoride
- •Ionite H
- •Euthymol Extraordinary Pink Whitening
- •POP Gel Whatzzup Watermelon
- •Himalaya PINK SALT Intensive Whitening Spearmint
- •OralLine Kids
- •FluoriMax 5000
- •CloSYS
- •Crest Bubblegum
- •Pro-Den Rx
- •MIPaste Plus Tutti Frutti
- •PCXX Peppermint Neutral GL
- •Made by Dentists Enamel Rebuilding Professional
- •First Chakra (Root) 7301
- •N01 Protomer
- •Neutramaxx 5000 TCP
- •Emmi-dent Fresh
- •TP COL OW Purple
- •Firefly Anticavity Fluoride
- •Bubble Fresh Toothpaste, with Fluoride
- •Top Quality Mfg APF
- •Crest 3D White Brilliance Pro Enamel Protect
- •Crest 3D White Advanced Luminous Mint
- •Crest 3D White Advanced Deep Clean
- •Crest Pro-Health Advanced Anti-Cavity Max Cavity
- •Crest Complete plus Whitening plus Scope
- •Listerine Smart Rinse Anticavity Fluoride Rinse - Mint Shield
- •Listerine Total Care Intense Anticavity Fluoride Mouthwash
- •evo Sensitive Whitening ANTI-Cavity Fluoride
- •Dentisse
- •Zonsen Gel Fluoride
- •Brush Buddies Crayola Anticavity Fluoride Bubblegum
- •Brush Buddies Crayola Anticavity Fluoride Strawberry
- •Made By Dentists, Inc. Rebuilding
- •Made by Dentists For Kids Cheetah Dust (Strawberry)
- •Made by Dentists Sensitive and Whitening Fresh Mint
- •Cool sense Care Plus
- •Kaylaan
- •Moon Platinum Advanced Whitening Anticavity
- •AutoBrush strawberry
- •Grape Bubblegum Flavor Sodium Fluoride Anticavity Toothpast
- •Enamur Fluoride AntiCavity Toothpast
- •Ortho Super Vanilla Fluoride Mouthwash
- •MySweetSmile Strawberry Toothpaste.
- •Dentalclean Regenerator Sensitive Kids
- •TheraBreath Complete Oral Rinse
- •Therabreath Whitening
- •AIM Whitening with Baking Soda
- •Essentials Healthy Teeth and Gums
- •Orajel Sensitivity Relief
- •60 Second Taste Strawberry
- •Dr Tichenors With Extra Whitening and Tartar Control
- •Wentworth Alcohol Free
- •Target Kids Watermelon Mint
- •Kolorz Sixty Second Fluoride FOAM Triple MINT
- •Kolorz Sixty Second Fluoride Triple MINT
- •Kolorz Sixty Second Fluoride Cherry Cheesecake
- •Colgate MaxFresh Citrus Fresh
- •Hello Kids Wild Strawberry Wild Strawberry
- •Colgate Triple Action
- •Crest Tartar Protection Fresh Mint Gel
- •Crest 3D White Arctic Fresh
- •Native Whitening
- •PreviDent OrthoDefense
- •Sensodyne Advanced Whitening
- •Sensodyne Pronamel Intensive Enamel Repair Whitening
- •Aquafresh Cavity Protection
- •Aquafresh Extreme Clean Pure Breath Action
- •HEB Gleaming White Fresh Mint
- •MediChoice Premium Anticavity Fluoride
- •ACT Restoring Anticavity Fluoride Mint Burst
- •ACT Whitening Anticavity Gentle Mint
- •POP Gel Pumpin Strawberry
- •Perioe Whitening Essentials 10X Charcoal Black Clean Mint
- •Toms Childrens Anticavity Mouthwash Silly Strawberry
- •Ocean Friends Anticavity Fluoride Watermelon Flavor
- •Kids Flouride Rinse
- •Just Right 5000
- •CloSYS Silver Sensitive Mouth Rinse Fluoride Rinse
- •Crest Complete Multi-Benefit Whitening plus Scope
- •Crest Kids SparkleFun Bubblegum
- •PCXX Vanilla Orange ONE Minute FM
- •PCXX Neutral RMS Bubblegum
- •Lornamead Natural White
- •Made by Dentists For Kids Eyeball Juice
- •Dental-Chord
- •DawnMist
- •Colgate Kids Mild Bubble Fruit Flavor
- •Colgate Deep Clean Fluoride
- •Colgate Optic White Relief
- •Colgate Optic White Charcoal
- •Colgate Optic White NON-HP Stain Fighter Fresh MINT
- •PRO-SYS
- •Gelato Neutral pH
- •Crest 3D White Advanced Charcoal
- •Crest 3D White Advanced Stain Shield
- •Crest 3D White Vibrant Mint
- •Crest 3D White Brilliance Luminous Purple
- •Crest Plus Tartar Protection
- •Crest Plus Whitening Deep Clean
- •Crest Complete plus Whitening
- •Listerine Smart Rinse Berry Splash
- •Listerine Smart Rinse Anticavity Fluoride Rinse - Bubble Blast
- •Listerine Clinical Solutions Enamel Strength Alpine Mint
- •Listerine Total Care Kids Anticavity Fluoride Rinse - Berry Splash
- •Crayola Anticavity Strawberry Flavor
- •Brush Buddies Crayola Anticavity Fluoride - Strawberry Flavor
- •Brush Buddies Crayola Swirl Anticavity Fluoride Watermelon Flavor
- •Brush Buddies Advanced Whitening ANTI-Cavity Fluoride Peppermint
- •Brush Buddies STAR WARS Anticavity Fluoride - Saber Strike Strawberry
- •Brush Buddies TOY Story Anticavity Fluoride - WILD WEST Watermelon
- •Brush Buddies Disney Frozen Anticavity Fluoride - Blizzard Berry
- •Brush Buddies Disney Princess Anticavity Fluoride - Grand Grape
- •GuruNanda Anti-Cavity
- •Acclean Anti-Cavity Sensitivity Relief
- •Sodium Fluoride 1.1% Dental Gel Bubblegum
- •Trader Joes
- •Multi-Vit-Flor
- •Denti Buongiorno GUM CARE Tooth
- •Made by Dentists For Kids Monster Slime Sour Apple
- •Made by Dentists Ultra Whitening Fresh Mint
- •Made by Dentist for Kids Chew Toy (Bubblegum)
- •Moon Whitening Gel Anticavity
- •Hismile Grape Bubblegum Flavor Sodium Fluoride Anticavity Toothpast
- •The Simpsons Purple Squishee Flavor Sodium Fluoride Anticavity Toothpast
- •Super Vanilla Fluoride Mouthwash
- •Super Chocolate Fluoride Mouthwash
- •Super Mint
- •Dentalclean Regenerator Sensitive Dental Gel with Flouride
- •Dentalclean Doctor Duck Kids Flouride Mouthwash
- •Crest 3D White Brilliance Bright Mint
- •Amerfresh Fluoride gel
- •Amerfresh Fluoride
- •Prime Tooth Care Summer Watermelon
- •TheraBreath for Kids Anticavity Wacky Watermelon
- •TheraBreath for Kids Anticavity Strawberry Splash
- •Pepsodent Complete Care Original
- •Signature Care Sensitive Maximum Strength
- •Kolorz Neutral Fluoride FOAM Triple MINT
- •Kroger Extra Whitening
- •Kroger Enamel Protection Sensitive Gentle Whitening
- •The Natural Dentist Groovy Grape
- •Colgate MaxFresh with Mini Breath Cool Mint
- •Colgate Sensitive Prevent and Repair
- •Colgate 2IN1 Whitening Stain Lifters
- •Colgate Junior Bubble Fruit
- •Crest 3D White Brilliance Charcoal
- •PreviDent 5000 Kids
- •Sensodyne
- •Aquafresh Extra Fresh PLUS Whitening
- •Sensodyne Pronamel Strong and Bright Enamel Mint
- •ACT Kids Anticavity Fluoride Wild Watermelon
- •ACT Total Care Anticavity Fluoride Icy Clean Mint
- •ACT Kids Berry Blast
- •Perioe Microbiome Whitening Cool Mint
- •Natural Fluoride Fresh Mint cavity protection whitening fresh breath
- •Opalescence Sensitivity Relief Whitening
- •Ionite APF Foam
- •Avant
- •Perioe Kakao KIDS Strawberry
- •Euthymol Whitening Purple Corrector
- •Euthymol Whitening
- •Maximum Security
- •Rexall Sensitive Freshmint
- •Maintenance Rinse Grape
- •PCXX Bubblegum APF G
- •PCXX Creme DE Menthe APF G
- •PCXX Watermelon APF G
- •PCXX Vanilla Orange Neutral GL
- •Colgate Cavity Protection Fresh Mint
- •60 Second Fluoride Gel
- •Firefly Strawberry Natural Fluoride
- •Scope Stay Strong
- •Crest Braces Care Anticavity Fluoride Rinse
- •Botao Kids Strawberry Flavored with Fluoride
- •Listerine Smart Rinse Anticavity Fluoride Rinse - Pink Lemonade Flavor
- •Listerine Total Care Alcohol Free Anticavity Fluoride Mouthwash Fresh Mint
- •Brush Buddies - Hot Wheels Anticavity Fluoride
- •Brush Buddies Crayola Anticavity Fluoride - Watermelon Flavor
- •Brush Buddies Mint Chocolate Chip Ice Cream Flavored Anticavity Fluoride
- •Sodium Fluoride 1.1% Dental Gel MINT
- •dentalux ANTI-Cavity Fluoride Whitening MINT
- •Denti Buongiorno GUM CARE COOL MINT Tooth
- •Brush Buddies Mouthwash Disney Cars Chow Cherry
- •Farmasi Whitening
- •Made By Dentists, Inc. Alien Blood
- •Made by Dentists for Kids Fluoride Anticavity Bamboolicious (Bubblegum)
- •Sensitive Mint Tooth-paste
- •Tidalove
- •Hismile Pink Lemonade Sodium Fluoride Anticavity Toothpast
- •Dentalclean Booster Kids
- •Zohar Anti Cavity Mouthwash Coolmint Flavour
- •Enamel Defense
- •Orajel SuperMario
- •Tanners Tasty Cha Cha Chocolate
- •Fluoride Mouth Rinse Anticavity
- •Kolorz Sixty Second Fluoride FOAM Cherry Cheesecake
- •Colgate Max Fresh Clean Mint
- •Colgate Minions Mild Bubble Fruit Fluoride
- •Colgate Optic White Stain Fighter Sens Relief
- •Intensive Enamel Repair Whitening TP
- •Topco Associates LLC Maximum Strength
- •TopCare Sensitive Extra Whitening
- •Crest 3D White Stain Shield
- •PreviDent 5000 Plus Fruitastic
- •Sensodyne Pronamel Intensive Enamel Repair Clean Mint
- •Sensodyne Pronamel Gentle Whitening
- •Sensodyne Pronamel Multi Action
- •HEB Enamel Protection Multi Action
- •ACT Kids Anticavity Fluoride Bubble Gum Blowout
- •ACT Anticavity Fluoride Kids Groovy Grape
- •ACT Kids Anticavity Fluoride Pineapple Punch
- •Meijer Enamel Guard
- •AVON Whitening Essentials 10X Charcoal Black Clean Mint
- •Perioe Whitening Essentials Fresh Aloe Green Mint
- •AVON Whitening Essentials Original Cool Mint
- •AVON Whitening Essentials Blanc Charcoal Fresh Mint
- •Crest Cavity Protection COOL MINT
- •Sound Body Sensitive Maximum Strength
- •Opal by Opalescence Sensitivity
- •CVS Enamel Guard
- •Koala Pals Berrylicious
- •Alpha-Pro
- •Allday 5000 Sensitive
- •Plaque Refresh Remineralizing Rinse Fresh Mint
- •Crest Strawberry
- •Gel 1100 Citrus
- •MIPaste One
- •Zooby Spearmint Safari
- •Walgreens Sensitive Enamel Repair
- •Crest Plus Baking Soda and Peroxide Whitening with Tartar Protection
- •Gerigentle-Good morning
- •Listerine Total Care Zero Alcohol Anticavity Fresh Mint
- •Listerine Clinical Solutions Teeth Strength Alpine Mint
- •Listerine Total Care Mild Alcohol Free Anticavity Fluoride Mouthwash
- •Brush Buddies Hot Wheels Anticavity Fluoride - Strawberry Flavor
- •Brush Buddies Cookies n Cream Ice Cream Flavored Anticavity Fluoride
- •Brush Buddies Mouthwash Toy Story Wild West Watermelon
- •Equate Glistening Mint
- •Hapee Gumtect Sensitive 100
- •The Simpsons Pink Donut Flavor Sodium Fluoride Anticavity Toothpast
- •Crest Pro-Health Advanced Multi-Protection
- •Dr. Jen SuperPaste Ortho
- •Prime Tooth Care Blueberry
- •Prime Tooth Care Strawberries
- •Advance White Tartar Control Breath Freshening
- •A and H Plus Therabreath Breath Freshners
- •Rite Aid Extra Whitening
- •Zap Neutral
- •Kolorz Sixty Second Fluoride FOAM Cotton Candy
- •Colgate MaxClean with Whitening Smartfoam
- •Colgate Kids Space Jam Mild Bubble Fruit Flavor
- •Colgate Max Fresh Cool Mint
- •Crest Baking Soda and Peroxide Whitening with Tartar Protection
- •Kids Crest Bubblegum Flavor
- •Crest Premium Plus Deep Clean Active Foam
- •Colgate Phos-Flur Ortho Defense Alcohol Free Anticavity Mint Fluoride
- •PreviDent 5000 Booster Plus Fruitastic
- •Sensodyne Pronamel Daily Protection
- •Sensodyne Pronamel Strong and Bright Enamel Extra Fresh
- •Sensodyne Natural white
- •Sensodyne Clinical White Intensive Clean
- •ACT Kids Anticavity Fluoride Groovy Grape
- •Beyond Activated Coconut Charcoal and Sea Salt
- •Toms Luminous White Fluoride Clean Mint cavity protection / whitening
- •Opal by Opalescence Original
- •Opalescence Whitening Sensitivity Relief
- •Ionite APF Neutral
- •Periosciences White Care AO Pro
- •SF 5000 Plus
- •SF
- •PCXX Neutral RNS Strawberry
- •Natural White Sensitive Enamel Guard Alpine Mint
- •Cavity Protection Fresh Mint Anticavity Mouthwash
- •Colgate Junior Mixed Kids Bubble Fruit Fluoride
- •Colgate Optic White NON-HP Stain Fighter Clean MINT
- •Firefly Bubble Gum natural fluoride
- •Quip Anticavity
- •Crest Cavity Protection Cool Mint Gel
- •Burts Bees Kids Strawberry Splash
- •Listerine Total Care Fresh Mint Anticavity
- •Brush Buddies Vanilla Ice Cream Flavored Anticavity Fluoride
- •Brush Buddies Crayola Color Changing Anticavity Fluoride Watermelon Flavor
- •TruGuard 5000
- •Denti Buongiorno Plaque CARE Tooth
- •meijer Sensitive Fresh MINT
- •Equate Sculpted White TP Equate Sculpted White TP
- •AutoBrush Bubblegum
- •Hismile Miffy Sweet Apple Flavor Sodium Fluoride Anticavity Toothpast
- •Watermelon Flavor Sodium Fluoride Anticavity Toothpast
- •OraPro Fluoride Anticavity
- •Super Mint Fluoride Mouthwash
- •Dubai Chocolate Flavor
- •Dentalclean Doctor Duck
- •Zohar Anti Cavity Mouthwash Bubble Gum Flavour
- •Willo Bubble Twist
- •Willo Berry Splash Dye Free
- •Bubble Gum Flavor For Kids 25g 50g
- •Seavue Anti-caries Gel
- •TheraBreath Kids Anticavity Oral Rinse Bubblegum
- •Advance White Extreme Whitening Tartar Control
- •Complete Care Whole Mouth Protection
- •Orajel KidsToothpaste
- •Orajel Paw Patrol
- •Orajel Gabbys Dollhouse
- •Rite Aid Enamel Guard
- •Denta 5000 Plus
- •Kolorz Sixty Second Fluoride FOAM BLUE Raspberry
- •Spry Dentifrice
- •Peppermint Twist
- •Colgate MaxFresh with Mini Breath Clean Mint
- •Colgate Sensitive plus Whitening
- •Colgate Sensitive Enamel Health
- •Colgate Kids Llama Mild Bubble Fruit Flavor
- •TP OW Stainfighter Clean Mint
- •Top Care Enamel Guard
- •Crest Cavity Protection Regular
- •Crest 3D White Radiant Mint
- •Crest 3D White Brilliance Blast
- •Crest Complete Multi-Benefit Whitening plus Cinnamon Expressions
- •Crest Complete Plus Scope Outlast
- •Sensodyne Pronamel mineral Boost whitening action
- •Sensodyne Pronamel Fresh Breath
- •Biotene Gentle Mint
- •Sensodyne Clinical White Stain Protector
- •Sensodyne Cavity and Sensitivity
- •HEB HEBuddy
- •Pearl White
- •Perioe Microbiome Total Care Strong Mint
- •Hello Unicorn Splash
- •Simply White Clean Mint
- •Atomy Propolis Toothpas TE 50G
- •Ionite R
- •Glowing White
- •Rexall Sensitive Extra Whitening
- •Davimet with Fluoride
- •Kids Kare
- •Gel 1100 Mint
- •MIPaste One Kids Bubble Gum
- •MIPaste Plus Mint
- •PCXX Peppermint APF F
- •Natural White Radiant White
- •Cavity Protection Fresh Mint
- •Ortho Guard
- •Neutramaxx 5000 PLUS Turbo
- •Dawnmist Fluoride
- •Darby APF Strawberry
- •Darby APF MINT
- •Handy Solutions Crest Complete Multi-Benefit Whitening plus Scope
- •Crest Pro-Health Advanced Complete Care Anticavity Fluoride
- •Crest 3D White Stain Eraser Icy Clean Mint
- •Crest Plus Cavity Protection Cool Mint Gel
- •Crest plus Tartar Protection Whitening
- •Crest 4in1
- •Crest Complete Plus Scope Outlast Ultra
- •Crest Complete Plus Active Fresh plus Whitening Scope
- •Brush Buddies Cars Anticavity Fluoride - KA-CHOW Cherry
- •Brush Buddies Barbie Anticavity Fluoride Bubblegum
- •Evo Sensitive Whitening Anti-cavity Fluoride Mouthwash
- •Eurofresh Whitening
- •Target UP AND UP Anticavity
- •Super Strawberry Fluoride Mouthwash
- •Super Chocolate
- •Dentalclean Sensitive Plus
- •Dentalclean Green Diamond Alcohol Free Mouthwash
- •Zohar Anti Cavity Mouthwash Fresh Mint Flavour
- •Willo Minty Mist Dye Free
- •Amerfresh Toothpowder
- •Prime Tooth Care Hami Melon
- •Kids Prime Pediatric Dental Group Anticavity for Kids
- •ME Mother Earth
- •Pop On Toothpaste.
- •Peroxicare
- •Sensitive Teeth and Gums
- •Orajel Kids Superman
- •Tanners Tasty Ooh La La Orange
- •Sodium Fluoride 5000 ppm Sensitive
- •Colgate Kids Minions Mouthwash
- •Optic White NON-HP Stain Fighter Clean MINT
- •Colgate Max Fresh Advanced Whitening
- •Kids Crest Bubblegum Rush
- •Crest 3D White Whitening Therapy Deep Clean Charcoal
- •Crest Pro-Health Advanced w/Extra Whitening
- •Crest Premium Plus Sensitivity Active Foam
- •Colgate Phos-Flur Ortho Defense Alcohol Free Anticavity Gushing Grape Fluoride
- •PreviDent 5000 Booster Plus Spearmint
- •PreviDent 5000 Plus Spearmint
- •Sensodyne Fresh Mint
- •Sensodyne Pronamel Kids Bubble Twist
- •Sensodyne Pronamel Kids Bubble Mint
- •ACT Kids Pure Protect Anticavity- Simply Strawberry
- •ACT Anticavity Fluoride Cinnamon
- •Clinpro Tooth Creme
- •Toms of Maine Deep Clean Spearmint
- •Opalescence Whitening
- •CVS Health Clinical White Stain Protector
- •Freshmint Premium Anticavity Gel
- •Freshmint Sensitive
- •Freshmint Anticavity Fluoride
- •CinnaFresh
- •Sensitive Tooth Polish
- •OralLine Secure
- •Multi-Vitamin Drops with Fluoride and Iron
- •MIPaste Plus Melon
- •PCXX Grape APF G
- •PCXX COOL Peppermint APF G
- •Made by Dentists Ultra Whitening Professional
- •Tap Water Detox 6018
- •DawnMist Gel Fluoride
- •Quip Anticavity Fluoride Concentrate
- •Sodium Fluoride and Potassium Nitrate
- •Crest Plus Cinnamon Expressions plus Whitening
- •Crest 3D White Stain Eraser Fresh Mint
- •Burts Bees Deep Clean plus Whitening
- •Burts Bees Extra White
- •Listerine Smart Rinse Anticavity Fluoride Rinse - Berry Splash
- •Listerine Total Care Fresh Mint Anticavity Fluoride
- •Crayola Anticavity Bubble GUM Flavor
- •Barbie Bubble Gum Anticavity Fluoride
- •Curodont Repair Fluoride PLUS
- •Plak Smacker Anti Cavity Fluoride
- •Zonsen Toothpaste,white
- •Cloveden Sensitive Care Tooth
- •Brush Buddies Mouthwash Spidey and Hist Amazing Friends Peter Parker Punch
- •Made by Dentists For Kids Alien Blood
- •Made by Dentists Enamel Rebuilding Fresh Mint
- •Classic Mint Flavor Sodium Fluoride Anticavity Toothpast
- •Tap Water Detox
- •Super Mint Prescription
- •Glorysmile Toothpaste.
- •MySweetSmile Mango Toothpaste.
- •Dentalclean Advance Pro
- •Prime Tooth Care Coconut Whip
- •Essentials Whiten and Strengthen
- •Tanners Tasty Vanilla Bling
- •DentaGel
- •Denta 5000 Plus Sensitive
- •Colgate Sensitive Complete Protection
- •Colgate Kids Maximum Cavity Protection
- •Hello Magical Mermaid
- •Hello Unicorn Sparkle
- •Hello Unicorn Splash unicorn splash anticavity fluoride rinse
- •Colgate Optic White Stain Fighter With Baking Soda
- •Crest Complete Multi Benefit Whitening plus Scope Outlast
- •Burts Bees Charcoal Peppermint
- •Crest Complete Plus 3 in 1
- •Crest Premium Plus Scope Outlast Active Foam
- •Crest Premium Plus Advanced Whitening Active Foam
- •PreviDent 5000 Dry Mouth
- •PreviDent Alcohol Free
- •PreviDent Very Berry
- •Sensodyne Extra Whitening
- •Aquafresh Sensitive Maximum Strength
- •Sensodyne Extra Whitening Cool Mint
- •Sensodyne Pronamel Active Shield Fresh Mint
- •Natean Clean plus Sensitivity Relief
- •Sensodyne Nourish Healthy White
- •Sensodyne Pronamel Gentle Whitening Advanced Plus
- •ACT Total Care Dry Mouth Anticavity Mouth
- •Perioe POP Complete Protection Prebiotic Mint Blast
- •Oratox
- •Sodium Fluoride Gel
- •Peppermint Charcoal Anticavity PCFT6 gently whitens teeth / fights cavities / safe for enamel / safe for everyday use
- •Opalescence Whitening Cool Mint
- •Ocean Friends Anticavity Fluoride Bubblegum Flavor
- •Exceed Total Care Sensitive Peppermint Tooth Polish
- •Sensitive Extra Whitening
- •CVS Pharmacy Enamel Guard
- •PRO Gel 5000 Mint
- •PRO Gel 5000 Citrus
- •MIPasteOne Kids Blue Raspberry
- •PCXX Strawberry APF F
- •PCXX Raspberry Neutral GL
- •PCXX Watermelon Neutral GL
- •PCXX Anticaries NO Flavor NE G
- •Made by Dentists For Kids Cheetah Dust
- •Made by Dentists Sensitive and Whitening Professional
- •Quality Choice Natural White
- •Colgate 2IN1 ICY Blast
- •Rembrandt Intense Stain
- •Crest Pro-Health Advanced Enamel Care
- •Crest 3D White Advanced Express White
- •Crest 3D White Brilliance Pro Rinse
- •Crest Premium Plus Active Foam Whitening scope
- •Listerine Total Care Kids Anticavity Fluoride Rinse Mint Shield
- •Brush Buddies Crayola Anticavity Fluoride - Bubble GUM Flavor
- •evo Advanced Whitening ANTI-Cavity Fluoride Peppermint
- •Brush Buddies Chocolate Ice Cream Flavored Anticavity Fluoride
- •Acclean Anti-Cavity
- •Plak Smacker Great White Shark
- •White Glo Professional White AntiCavity
- •Brush Buddies Squishmallows Anticavity Fluoride MINT Falvor
- •Brush Buddies Mouthwash 12oz Star Wars Saber Strike Strawberry
- •Made By Dentists, Inc. Monster Slime
- •Sensitive Whitening Tooth-paste
- •Auraglow Whitening
- •Moon Charcoal Whitening Anticavity
- •AutoBrush Watermelon
- •Super Chocolate Prescription
- •Ortho Super Chocolate Fluoride Mouthwash
- •Super Vanilla
- •Super Strawberry
- •MySweetSmile Toothpaste.
- •Dentalclean Dr. Duck Strawberry flouride Mouthwash
- •Crest 3D White Sparkle Mint
- •Fluoride Anti Caries 65g Coconut Whip Juicy Peach Mango Smoothie Summer Watermelon Hami Melom Cream Strawberries Blueberry
- •Prime Tooth Care Juicy Peach
- •Prime Tooth Care Mango Smoothie
- •Glister Multi-Action
- •TheraBreath
- •AIM Cavity Protection Multi Benefit
- •AIM Tartar Control Plus Mouthwash and Whitening
- •Orajel Complete Protection
- •Orajel Toy Story 5 Anticavity
- •Sodium Fluoride 5000 ppm Dry Mouth
- •Target Sensitive Whitening TP
- •Kolorz Sixty Second Fluoride Cotton Candy
- •Kolorz Sixty Second Fluoride BLUE Raspberry
- •Colgate Maximum Cavity Protection Bubble Fruit Flavor
- •Colgate Ultra White Charcoal
- •Colgate Sparkling White Cinnamint
- •Colgate Optic White Stain Fighter Fresh Mint
- •Colgate Optic White Stain Fighter Clean Mint
- •Crest 3D White Luxe Diamond Strong
- •Burts Bees Extra White Zen Peppermint
- •Crest Premium Plus Scope Dual Blast Active Foam
- •Sensodyne Pronamel Gentle Whitening Advanced
- •Sensodyne Pronamel Clinical Enamel Strength Deep Clean
- •Sensodyne Pronamel Clinical Enamel Strength Whitening Action
- •Sensodyne Advanced Whitening Plus
- •HEB Sensitive Extra Whitening Twin
- •ACT Anticavity Fluoride Kids Bubblegum
- •Dentox
- •Toms Whole Care Mouthwash Fresh Mint
- •CVS Health Sensitive Enamel Repair
- •Universal Sensitive ANTI-Cavity Fluoride
- •DG health Sensitive Maximum Strength
- •Allday 5000
- •FluoriMax 5000 Sensitive
- •CloSYS Fluoride Rinse
- •Crest 3D White Fresh Mint
- •CVS Extra Whitening
- •Maintenance Rinse Mint
- •Maintenance Rinse Citrus
- •Treatment Rinse Mint
- •MIPaste One Kids Cotton Candy
- •MIPaste Plus Vanilla
- •PCXX Neutral RNS Grape
- •PCXX Neutral RNS Peppermint
- •PCXX Marshmallow APF G
- •Made by Dentists For Kids Monster Slime
- •Zooby Happy Hippo Cake
- •Neutra MAXX 5000
- •Emmi-dent Whitening
- •Walgreens Sensitive Extra Whitening
- •Quip
- •Sodium Fluoride 5000 Plus
- •Crest 3D White Advanced Radiant Mint
- •Crest 3D White Advanced Whitening
- •Crest 3D White Glamorous White
- •Crest 3D White Stain Eraser Polishing Mint
- •Listerine Total Care Kids Anticavity Fluoride Rinse Bubble Blast
- •Listerine Total Care Extra Mild Alcohol Free Anticavity Fluoride Mouthwash
- •Crayola Anticavity Watermelon Flavor
- •Brush Buddies Oral Rinse Sparkle Mint
- •evo Sensitive ANTI-Cavity Fluoride Sweet MINT
- •ARU Cavity Protection
- •Brush Buddies Spidey and his Amazing Friends Anticavity Fluoride-Spidey Punch
- •Charm Tex Fluoride Gel
- •dentalux Sensitive ANTI-Cavity Fluoride
- •Wintergreen Peppermint
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 3 sectors as 5 functional roles.
- •Alloys in Primary Metal Manufacturing (100%)Use—non-incorporative activities
- •Flux agent in All Other Basic Inorganic Chemical Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
Chemical Identity
CAS7681-49-4
PubChem CID5235
DTXSIDDTXSID2020630
FormulaFNa
Mol. Weight41.9881724 g/mol
SMILES[F-].[Na+]
Data Sources
- EPA CompTox (DSSTox) · DTXSID2020630Retrieved 2026-04-06
- PubChem · compound 5235Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Sodium fluoride (CAS 7681-49-4) https://chemicalindependence.com/chemical/7681-49-4/ EPA CompTox (DSSTox): DTXSID2020630. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2020630 PubChem: 5235. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/5235 EPA Chemical Data Reporting: 7681-49-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 7681-49-4. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 282619 for CAS 7681-49-4. Reporting year: 2024. https://usatrade.census.gov/