Hydrogen fluoride
Drug ingredientCAS 7664-39-3
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$170M
Top sourceMexico 83%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 281111 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
MX 83%MexicoTW 6%TaiwanJP 3%JapanES 3%SpainDE 2%Germany
- Canada
- Belgium
- Norway
- Colombia
EPA-registered manufacturers (8)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Nutrien · CA Canada
Advance Research Chemicals
Brainerd Chemical
Dupont Specialty Products Usa
Ge Vernova
Show all 8
Nutrien Us Top
Transene
Transene Company, Inc. Danvers
Domestic parents -- activity not disclosed (9)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
3M
Chemours
Daikin America
Entegris
Harcros Chemicals
Show all 9
Honeywell International (123312)
Icl Specialty Products North America
Norman, Fox &
Polyventive
EPA-registered importers (24)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Asia Union Electronic Chemical · TW Taiwan
Fujifilm Holding Japan · JP Japan
Sojitz · JP Japan
Arkema
Asia Union Electronic Chemicals - Reno
Show all 24
Avantor
Brenntag
Brenntag Global Marketing
Cascade Columbia
Chemical Distribution Network
Fujifilm Holdings America
Global Chemical Resources
Henkel
Hf Sinclair
Ideal Chemical & Supply
Industrial Chemicals
Kanto
Lanxess
Mexichem Fluor
Sojitz Corporation Of America
Special Materials
Unique Chemical Technologies
Valudor Products
Wego Chemical Group
Why It Matters
Sectors
HealthEnergyElectronicsTransportationConstructionMetals & MiningConsumer ProductsCore Chemicals
Downstream Uses
Appears in 37 drug and cosmetic product listings (FDA).
- •Heavy Metal Detox
- •Hemorrhoids
- •D3 Organ Support
- •Acidum Fluoricum
- •Boneforce HP
- •Age Defiance Pro
- •Bone Support HP
- •Bestmade Natural Products BM159
Show all 37
- •Vascular HP
- •Hydrofluoricum acidum
- •Hair-Scalp
- •Cataracc
- •Scars-Adhesions
- •D10 SKN-DRN
- •OHM Fatigue Relief
- •Acne Relief
- •Dentastat
- •BONE HP
- •Lactistat
- •Alpha-Pro
- •H.M.D.
- •Detox III
- •Dentaforce
- •HAIR STIM
- •Varicose Veins
- •CardCare
- •BHI Skin
- •Pollutox
- •Thyroid Tonic
- •Joette Calabrese Survivalist Kit
- •Thyropro
- •Bestmade Natural Products Fluor Acid
- •Venoforce I
- •C02 Fibrozolve
- •Alumizen
- •Heavy Metal-Amalga Detox
- •A01 Cellular Recharge
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 14 sectors as 10 functional roles.
- •Etching agent in Computer and Electronic Product Manufacturing (100%)Use—non-incorporative activities
- •Plating agent in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Etching agent in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (70%)Processing as a reactant
- •Etching agent in Fabricated Metal Product Manufacturing (30%)Use—non-incorporative activities
- •Intermediate in Industrial Gas Manufacturing (100%)Processing as a reactant
- •Etching agent in All Other Basic Inorganic Chemical Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Brightener in All Other Basic Inorganic Chemical Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Transportation Equipment Manufacturing (37%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Fabricated Metal Product Manufacturing (62%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Computer and Electronic Product Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Electrical Equipment, Appliance, and Component Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Machinery Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Fabricated Metal Product Manufacturing (62%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Machinery Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Computer and Electronic Product Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Transportation Equipment Manufacturing (37%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Electrical Equipment, Appliance, and Component Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in All Other Basic Inorganic Chemical Manufacturing (65%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Inorganic Chemical Manufacturing (35%)Processing as a reactant
- •Intermediate in Pharmaceutical and Medicine Manufacturing (100%)Processing as a reactant
- •Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
- •Chemical reaction regulator in All Other Basic Inorganic Chemical Manufacturing (100%)Processing as a reactant
- •Plating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •Etching agent in All Other Chemical Product and Preparation Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •Brightener in Wholesale and Retail Trade (4%)Processing—incorporation into formulation, mixture, or reaction product
- •Brightener in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (87%)Processing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Petroleum RefineriesUse—non-incorporative activities
- •Catalyst in All Other Basic Inorganic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation ManufacturingProcessing as a reactant
- •Intermediate in All Other Chemical Product and Preparation ManufacturingProcessing as a reactant
- •Semiconductor and photovoltaic agent in Computer and Electronic Product Manufacturing (100%)Use—non-incorporative activities
- •Chemical reaction regulator in Petroleum Refineries (100%)Use—non-incorporative activities
Chemical Identity
CAS7664-39-3
PubChem CID14917
DTXSIDDTXSID1049641
FormulaFH
Mol. Weight20.0064 g/mol
SMILESF
Data Sources
- EPA CompTox (DSSTox) · DTXSID1049641Retrieved 2026-04-06
- PubChem · compound 14917Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Hydrogen fluoride (CAS 7664-39-3) https://chemicalindependence.com/chemical/7664-39-3/ EPA CompTox (DSSTox): DTXSID1049641. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1049641 PubChem: 14917. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/14917 EPA Chemical Data Reporting: 7664-39-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 7664-39-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 281111 for CAS 7664-39-3. Reporting year: 2024. https://usatrade.census.gov/