Hydrochloric acid
Drug ingredientCAS 7647-01-0
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$70M
Top sourceCanada 83%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 280610 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
CA 83%CanadaJP 5%JapanDE 4%GermanyTW 2%TaiwanCO 2%Colombia
- Belgium
- Peru
- India
- Ireland
- Netherlands
- Austria
- Switzerland
- United Kingdom
- Italy
- Norway
- South Africa
EPA-registered manufacturers (53)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Bayer Ag · DE Germany
China National Chemical · CN China
Ineos · IM Isle of Man
Italmatch Chemicals Spa · IT Italy
Show all 53
Shin-Etsu Chemical · JP Japan
Syensqo Sa · BE Belgium
Umicore Sa · BE Belgium
3M
Amvac Chemical
Arkema
Asphalt And Fuel Supply
Basf
Bayer Us Holding
Brainerd Chemical
Cabot
Carbonfree Chemicals Spe 1 Holdings
Cargill, Incorporated
Corning
Corning Incorporated
Covestro
Dover Chemical
Dow Chemical
Evonik
Formosa Plastics Corporation, U.S.A.
Heraeus Metal Processing
Honeywell International (123312)
Huntsman
Iff Chemical Holdings
Ineos Enterprises Us Hold
Jones-Hamilton
Kuehne Chemical
Lanxess
Louisiana Pigment
Macdermid
Magnetics International
Mexichem Fluor
Nippon Paper Industries Usa
Occidental Petroleum
Olin
Pvs Chemicals
Pvs Technologies
Samsung Austin Semiconductor
Shintech Louisiana
Solvay
Syngenta Crop Protection
The El
Tri-Chem Industries
Trinity Manufacturing
Tronox Us Holdings
Umicore Usa
Vandemark Chemical
Westlake
Domestic parents -- activity not disclosed (19)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Albemarle
Calfrac Well Services
Chemours
Corteva Agriscience
Daikin America
Show all 19
Emd Holding
Erco (Us) Holdings
Harcros Chemicals
Hawkins
Icl Specialty Products North America
Life Technologies
Milliken &
Minerals Technologies
Polymer Additives
Polyventive
Pvs Dx
S.C. Johnson & Son
Schlumberger
United Refining
EPA-registered importers (15)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Asia Union Electronic Chemical · TW Taiwan
Azelis S A · LU Luxembourg
Chemtrade Logistics · CA Canada
Amphenol
Asia Union Electronic Chemicals - Reno
Show all 15
Avantor
Azelis Us Holdings
Bei Hawaii
Cascade Columbia
Chemtrade Holdco Us Inc (Electrochem)
Kanto
Kronos Worldwide
Mays Chemical Company Of Puerto Ri
Thermo Fisher Scientific
Wintersun International
18 FDA-registered drug labelers
Bestmade Natural Products
BioActive Nutritional, Inc.
Boiron
Deseret Biologicals, Inc.
Detrex Corporation
DNA Labs
Energique, Inc
Hahnemann Laboratories, INC.
Herbamed AG
King Bio Inc.
MediNatura Inc
Micro Balance Health Products
Natural Creations, Inc
Nutritional Specialties, Inc.
OHM PHARMA INC.
Professional Complementary Health Formulas
Seroyal USA
Silver Star Brands
Why It Matters
Sectors
FoodPlastics & RubberElectronicsPaper & PrintingCore ChemicalsHealthEnergyConsumer ProductsMetals & MiningWaterTextilesAgricultureConstruction
Downstream Uses
Appears in 24 drug and cosmetic product listings (FDA).
- •Habit
- •Muriaticum acidum
- •Acidum Muriaticum
- •Evtox
- •Skin Irritations and Itch Relief
- •Stress Away Anxiety Relief
- •Bestmade Natural Products BM76
- •Bestmade Natural Products BM182 Pellets
Show all 24
- •D-114
- •Bestmade Natural Products BM62
- •Oral Health
- •REFL HS
- •Ahh Sleep
- •Fungisode
- •Endotoxin Terrain Drops 2143
- •Joette Calabrese Survivalist Kit
- •Stomach Enzyme Formula
- •BHI Hemorrhoid
- •Hemorrhoid
- •CV TOX
- •Abdominal Pain Drops 2051
- •Bestmade Natural Products BM182
- •EPST PLUS
- •Fatigue Stat CM
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 29 sectors as 20 functional roles.
- •Intermediate in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Processing aids, specific to petroleum production in Petrochemical ManufacturingProcessing as a reactant
- •Plating agent in Primary Metal ManufacturingProcessing as a reactant
- •Cleaning agent in Food, beverage, and tobacco product manufacturingUse—non-incorporative activities
- •Semiconductor and photovoltaic agent in Computer and Electronic Product Manufacturing (100%)Processing—repackaging
- •Processing aids, specific to petroleum production in Oil and Gas Drilling, Extraction, and Support activities (20%)Use—non-incorporative activities
- •Etching agent in Computer and Electronic Product Manufacturing (100%)Processing as a reactant
- •pH regulating agent in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—repackaging
- •Surfactant (surface active agent) in All Other Basic Inorganic Chemical Manufacturing (36%)Processing as a reactant
- •Solids separation (precipitating) agent, not otherwise specified in Agriculture, Forestry, Fishing and Hunting (25%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Inorganic Chemical Manufacturing (34%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Pharmaceutical and Medicine Manufacturing (5%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Plastics Material and Resin Manufacturing (86%)Processing as a reactant
- •Cleaning agent in Oil and Gas Drilling, Extraction, and Support activities (100%)Use—non-incorporative activities
- •Cleaning agent in Electrical Equipment, Appliance, and Component Manufacturing (100%)Processing as a reactant
- •Anti-freeze agent in Utilities (1%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in All Other Basic Organic Chemical ManufacturingUse—non-incorporative activities
- •Drier in Computer and Electronic Product Manufacturing (100%)Processing as a reactant
- •Cleaning agent in Petroleum Refineries (100%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in All Other Chemical Product and Preparation Manufacturing (10%)Processing—repackaging
- •Emulsifier in Asphalt Paving, Roofing, and Coating Materials Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Fabricated Metal Product Manufacturing (100%)Use—non-incorporative activities
- •Intermediate in Paper Manufacturing (100%)Processing as a reactant
- •pH regulating agent in Wholesale and Retail Trade (100%)Processing as a reactant
- •Intermediate in Not Known or Reasonably AscertainableUse—non-incorporative activities
- •Processing aids, specific to petroleum production in Petroleum Refineries (100%)Processing as a reactant
- •Intermediate in All Other Basic Organic Chemical Manufacturing (73%)Processing as a reactant
- •pH regulating agent in Oil and Gas Drilling, Extraction, and Support activities (6%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Primary Metal Manufacturing (6%)Processing—incorporation into formulation, mixture, or reaction product
- •Processing aids, specific to petroleum production in All Other Basic Organic Chemical Manufacturing (24%)Processing as a reactant
- •pH regulating agent in Utilities (62%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (21%)Processing as a reactant
- •pH regulating agent in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant
- •Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (0%)Use—non-incorporative activities
- •Etching agent in Primary Metal Manufacturing (2%)Processing as a reactant
- •Catalyst in All Other Basic Inorganic Chemical Manufacturing (0%)Processing as a reactant
- •pH regulating agent in Printing Ink ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Food, beverage, and tobacco product manufacturingUse—non-incorporative activities
- •pH regulating agent in Other (100%)Use—non-incorporative activities
- •Intermediate in Wholesale and Retail TradeProcessing—repackaging
- •Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Solubility enhancer in Oil and Gas Drilling, Extraction, and Support activitiesProcessing as a reactant
- •pH regulating agent in Miscellaneous ManufacturingProcessing as a reactant
- •Intermediate in Food, beverage, and tobacco product manufacturingProcessing as a reactant
- •Plating agent in Fabricated Metal Product ManufacturingProcessing as a reactant
- •Oxidizing agent in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
- •Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (1%)Not Known or Reasonably Ascertainable
- •Plating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (2%)Not Known or Reasonably Ascertainable
- •Cleaning agent in Paper Manufacturing (1%)Not Known or Reasonably Ascertainable
- •Processing aids, specific to petroleum production in Services (2%)Not Known or Reasonably Ascertainable
- •Oxidizing agent in All Other Basic Inorganic Chemical Manufacturing (100%)Use—non-incorporative activities
- •Catalyst in All Other Basic Organic Chemical Manufacturing (10%)Processing as a reactant
- •Intermediate in Primary Metal ManufacturingProcessing as a reactant
- •Oxidizing agent in Plastics Material and Resin ManufacturingProcessing as a reactant
- •Intermediate in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Diluent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (12%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Services (14%)Use—non-incorporative activities
- •Cleaning agent in Construction (0%)Use—non-incorporative activities
- •Diluent in All Other Chemical Product and Preparation Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Services (3%)Use—non-incorporative activities
- •pH regulating agent in Electrical Equipment, Appliance, and Component Manufacturing (33%)Use—non-incorporative activities
- •Cleaning agent in Utilities (0%)Use—non-incorporative activities
- •pH regulating agent in Pharmaceutical and Medicine Manufacturing (13%)Use—non-incorporative activities
- •pH regulating agent in Machinery Manufacturing (2%)Use—non-incorporative activities
- •pH regulating agent in Fabricated Metal Product Manufacturing (1%)Use—non-incorporative activities
- •Etching agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Oxidizing agent in Petrochemical Manufacturing (0%)Processing as a reactant
- •Processing aids, specific to petroleum production in Wholesale and Retail Trade (0%)Processing—repackaging
- •pH regulating agent in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Use—non-incorporative activities
- •Solvent in Primary Metal Manufacturing (10%)Processing—repackaging
- •Pigment in Synthetic Dye and Pigment Manufacturing (100%)Use—non-incorporative activities
- •Bleaching agent in Miscellaneous Manufacturing (4%)Use—non-incorporative activities
- •Semiconductor and photovoltaic agent in Industrial Gas ManufacturingUse—non-incorporative activities
Chemical Identity
CAS7647-01-0
PubChem CID313
DTXSIDDTXSID2020711
FormulaClH
Mol. Weight36.46 g/mol
SMILESCl
Data Sources
- EPA CompTox (DSSTox) · DTXSID2020711Retrieved 2026-04-06
- PubChem · compound 313Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Hydrochloric acid (CAS 7647-01-0) https://chemicalindependence.com/chemical/7647-01-0/ EPA CompTox (DSSTox): DTXSID2020711. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2020711 PubChem: 313. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/313 EPA Chemical Data Reporting: 7647-01-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 7647-01-0. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 280610 for CAS 7647-01-0. Reporting year: 2024. https://usatrade.census.gov/